Recombinant human Granzyme K protein | NKMAX ATGP3539 product information

product summary

company name :

NKMAX

product type :

protein

product name :

Recombinant human Granzyme K protein

catalog :

ATGP3539

quantity :

10 ug

price :

80 USD

more info or order :

NKMAX product webpage

product information

Product Type :

Proteins

Item Name :

Recombinant human Granzyme K protein

Domain :

27-264aa

Catalog number (SKU) :

ATGP3539

NCBI :

NP_002095.1

Description :

GZMK, as known as Granzyme K, is a member of a group of related serine proteases from the cytoplasmic granules of cytotoxic lymphocytes. Cytolytic T lymphocytes (CTL) and natural killer (NK) cells share the remarkable ability to recognize, bind, and lyse specific target cells. They are thought to protect their host by lysing cells bearing on their surface 'nonself' antigens, usually peptides or proteins resulting from infection by intracellular pathogens. The protein described here lacks consensus sequences for N-glycosylation present in other granzymes. Recombinant human GZMK, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.

Alternative Names :

Granzyme K, GZMK, TRYP2, GZMK, PRSS, tryptase II, Fragmentin-3, Granzyme-3, NK-tryptase-2, NK-Tryp-2

Concentration :

0.25mg/ml (determined by absorbance at 280nm)

Formulation :

Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 20% glycerol, 1mM DTT

Storage :

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

General References :

Jiang W., et al, (2011) J. Immunol. 187:781-790.;; Wensink AC., et al, (2014) Proc. Natl. Acad. Sci. U.S.A. 111:5974-5979.

Purity :

> 95% by SDS-PAGE

Applications :

SDS-PAGE

Antigen Species :

Human

Gene Category :

Apoptosis

Molecular Weight :

26.9 kDa (247aa)

Endotoxin :

< 1 EU per 1ug of protein (determined by LAL method)

Amino Acid Sequence :

IIGGKEV SPHSRPFMAS IQYGGHHVCG GVLIDPQWVL TAAHCQYRFT KGQSPTVVLG AHSLSKNEAS KQTLEIKKFI PFSRVTSDPQ SNDIMLVKLQ TAAKLNKHVK MLHIRSKTSL RSGTKCKVTG WGATDPDSLR PSDTLREVTV TVLSRKLCNS QSYYNGDPFI TKDMVCAGDA KGQKDSCKGD SGGPLICKGV FHAIVSGGHE CGVATKPGIY TLLTKKYQTW IKSNLVPPHT N

Tag :

His-Tag

Expression System :

Baculovirus

Predicted nterm :

Ala

Product Type Name :

Recombinant Protein

UniProt No. :

P49863

Internal Search Terms :

GZMK,ATGP3539-10ug,ATGP3539-20ug,ATGP3539-50ug,ATGP3539-100ug,ATGP3539-250ug,ATGP3539-500ug,ATGP3539-1mg,ATGP3539-10,ATGP3539-20,ATGP3539-50,ATGP3539-100,ATGP3539-250,ATGP3539-500,ATGP3539-1

more info or order :

NKMAX product webpage