protein

Recombinant human TNFRSF27/EDA2R protein

ATGP3531

10 ug

80 USD

Recombinant human TNFRSF27/EDA2R protein

1-138aa

ATGP3531

NP_001229239

EDA2R also known as Tumor necrosis factor receptor superfamily member 27 isoform 2, is a transmembrane protein in the TNF receptor superfamily. This protein itself is strongly associated with androgenetic alopecia (male hair loss). It is widely expressed, notably in embryonic basal epidermal cells and maturing hair follicles. Even though it does not contain a cytoplasmic death domain, it can associate with Fas and induce EDA-A2 dependent apoptosis. Recombinant human EDA2R protein, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.

EDA2R, EDA-A2 receptor, EDAA2R, EDA-A2R, TNFRSF27, Tumor necrosis factor receptor superfamily member 27 isoform 2, XEDAR, X-linked ectodysplasin-A2 receptor

0.5mg/ml (determined by absorbance at 280nm)

Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 20% glycerol, 1mM DTT

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Brosh R., et al. (2010) FEBS Lett. 584:2473-2477;; Redler S., et al. (2012) Br J Dermatol. 166:1314-1318

> 90% by SDS-PAGE

SDS-PAGE

Human

Apoptosis

42.5 kDa (380aa)

< 1 EU per 1ug of protein (determined by LAL method)

MDCQENE YWDQWGRCVT CQRCGPGQEL SKDCGYGEGG DAYCTACPPR RYKSSWGHHR CQSCITCAVI NRVQKVNCTA TSNAVCGDCL PRFYRKTRIG GLQDQECIPC TKQTPTSEVQ CAFQLSLVEA DAPTVPPQEA T

hIgG-His-Tag

Baculovirus

Ala

Recombinant Protein

Q9HAV5

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