Recombinant human chorionic gonadotropin subunit beta/CGB protein

product summary

company name :

NKMAX

product type :

protein

product name :

Recombinant human chorionic gonadotropin subunit beta/CGB protein

catalog :

ATGP3529

quantity :

10 ug

price :

150 USD

more info or order :

NKMAX product webpage

product information

Product Type :

Proteins

Item Name :

Recombinant human chorionic gonadotropin subunit beta/CGB protein

Domain :

21-165aa

Catalog number (SKU) :

ATGP3529

NCBI :

NP_000728

Description :

CGB3, also known as choriogonadotropin subunit beta, is a member of the glycoprotein hormone beta chain family and encodes the beta 3 subunit of chorionic gonadotropin (CG). It stimulates the expression of GCM1 target genes, including the fusogenic protein syncytin-1, to promote placental cell fusion. It synthesized in large quantities by the developing placenta, reaching peak concentrations in maternal blood during the late first trimester and early midtrimester of pregnancy. It is expressed exclusively by trophoblasts. It is an important biomarker in pregnancy and oncology, where it is routinely detected and quantified by specific immunoassays. Recombinant human CGB3, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.

Alternative Names :

Choriogonadotropin subunit beta, CGB3, CGB, CGB5, CGB7, CGB8, hCGB

Concentration :

0.25mg/ml (determined by absorbance at 280nm)

Formulation :

Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 20% glycerol

Storage :

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

General References :

Cheong ML., et al. (2015) Mol Cell Biol. 36:197-209.;; Gregor CR., et al. (2011) J Biol Chem. 286:25016-25026.

Purity :

> 90% by SDS-PAGE

Applications :

SDS-PAGE

Antigen Species :

Human

Gene Category :

Signal Transduction

Molecular Weight :

16.6 kDa (154aa)

Endotoxin :

< 1 EU per 1ug of protein (determined by LAL method)

Amino Acid Sequence :

SKEPLRP RCRPINATLA VEKEGCPVCI TVNTTICAGY CPTMTRVLQG VLPALPQVVC NYRDVRFESI RLPGCPRGVN PVVSYAVALS CQCALCRRST TDCGGPKDHP LTCDDPRFQD SSSSKAPPPS LPSPSRLPGP SDTPILPQ

Tag :

His-Tag

Expression System :

Baculovirus

Predicted nterm :

Ala

Product Type Name :

Recombinant Protein

UniProt No. :

P0DN86

Internal Search Terms :

CGB3, Choriogonadotropin subunit beta, CGB3, CGB, CGB5, CGB7, CGB8, hCGB,ATGP3529-10ug,ATGP3529-20ug,ATGP3529-50ug,ATGP3529-100ug,ATGP3529-250ug,ATGP3529-500ug,ATGP3529-1mg,ATGP3529-10,ATGP3529-20,ATGP3529-50,ATGP3529-100,ATGP3529-250,ATGP3529-500,ATGP3529-1

more info or order :

NKMAX product webpage