product summary
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company name :
NKMAX
product type :
protein
product name :
Recombinant mouse Histone Deacetylase 8/HDAC8 protein
catalog :
ATGP3515
quantity :
10 ug
price :
240 USD
more info or order :
product information
Product Type :
Proteins
Item Name :
Recombinant mouse Histone Deacetylase 8/HDAC8 protein
Domain :
1-377aa
Catalog number (SKU) :
ATGP3515
NCBI :
NP_081658
Description :
Hdac8, also known as histone deacetylase 8 isoform 1, is a member of the class I Histone Deacetylases. Its specific inhibition reduces gene expression and production of proinflammatory cytokines in vitro and in vivo. It expressed in the renal epithelial cells of the mouse kidney. Its activity contributes to renal protection and functional recovery and is required for renal regeneration after AKI. Recombinant mouse Hdac8, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.
Alternative Names :
Histone deacetylase 8 isoform 1, Hdac8, 2610007D20Rik, HD8, Protein deacetylase HDAC8, Protein decrotonylase HDAC8
Concentration :
0.25mg/ml (determined by absorbance at 280nm)
Formulation :
Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol
Storage :
Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
General References :
Li S., et al. (2015) J Biol Chem. 290:2368-2378.;; Tang J., et al. (2014) Am J Physiol Renal Physiol. 307:F303-316.
Purity :
> 90% by SDS-PAGE
Applications :
SDS-PAGE
Antigen Species :
Mouse
Gene Category :
Epigenomics (Transcription & Translation)
Molecular Weight :
42.5 kDa (383aa)
Endotoxin :
< 1 EU per 1ug of protein (determined by LAL method)
Amino Acid Sequence :
MEMPEEPANS GHSLPPVYIY SPEYVSICDS LVKVPKRASM VHSLIEAYAL HKQMRIVKPK VASMEEMATF HTDAYLQHLQ KVSQEGDEDH PDSIEYGLGY DCPATEGIFD YAAAIGGGTI TAAQCLIDGK CKVAINWSGG WHHAKKDEAS GFCYLNDAVL GILRLRRKFD RILYVDLDLH HGDGVEDAFS FTSKVMTVSL HKFSPGFFPG TGDMSDVGLG KGRYYSVNVP IQDGIQDEKY YHICESVLKE VYQAFNPKAV VLQLGADTIA GDPMCSFNMT PVGIGKCLKY VLQWQLATLI LGGGGYNLAN TARCWTYLTG VILGKTLSSE IPDHEFFTAY GPDYVLEITP SCRPDRNEPH RIQQILNYIK GNLKHVV
Tag :
His-Tag
Expression System :
Baculovirus
Predicted nterm :
Met1
Product Type Name :
Recombinant Protein
UniProt No. :
Q8VH37
Internal Search Terms :
Hdac8, Histone deacetylase 8 isoform 1, Hdac8, 2610007D20Rik,ATGP3515-10ug,ATGP3515-20ug,ATGP3515-50ug,ATGP3515-100ug,ATGP3515-250ug,ATGP3515-500ug,ATGP3515-1mg,ATGP3515-10,ATGP3515-20,ATGP3515-50,ATGP3515-100,ATGP3515-250,ATGP3515-500,ATGP3515-1
more info or order :
company information
NKMAX
SNUH Health Care Innovation Park 6F
172 Dolma-ro, Bundang-gu
Seongnam-si, Gyeonggi-do
https://www.nkmaxbio.com
82-31-8017-8114
headquarters: South Korea
NKMAX Co. Ltd. is a biotech company that manufactures and supplies a unique line of quality proteins and antibodies worldwide to both researchers and retailers.