Recombinant human VE-Cadherin/CDH5 protein | NKMAX ATGP3506 product information

product summary

company name :

NKMAX

product type :

protein

product name :

Recombinant human VE-Cadherin/CDH5 protein

catalog :

ATGP3506

quantity :

10 ug

price :

80 USD

more info or order :

NKMAX product webpage

product information

Product Type :

Proteins

Item Name :

Recombinant human VE-Cadherin/CDH5 protein

Domain :

29-599aa

Catalog number (SKU) :

ATGP3506

NCBI :

NP_001786.2

Description :

CDH5, as known as cadherin-5, is a member of the atypical/type 2 subgroup of Cadherin homophilic adhesion proteins. This protein plays a role in the formation, maturation and remodeling of the vascular wall. It is widely considered to be specific for vascular endothelia in which it is either the sole or the predominant cadherin, often co-existing with N-cadherin. Also, this protein regulates or is regulated by VEGF R2, type 1 and type 2 TGF-beta receptors, and other endothelial junction proteins such as JAM-C, Claudin-5, and N-Cadherin. Recombinant human CDH5, fused to hIgG-His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.

Alternative Names :

Cadherin-5, CDH5, 7B4, CD144, Vascular endothelial cadherin

Concentration :

0.5mg/ml (determined by absorbance at 280nm)

Formulation :

Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol

Storage :

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

General References :

Yan Z., et al, (2016) Arterioscler. Thromb. Vasc. Biol. 36:339-349.;; Timmerman I., et al, (2015) J. Cell. Sci. 128:3041-3054.

Purity :

> 90% by SDS-PAGE

Applications :

SDS-PAGE

Antigen Species :

Human

Gene Category :

Signal Transduction

Molecular Weight :

91.5 kDa (810aa)

Endotoxin :

< 1 EU per 1ug of protein (determined by LAL method)

Amino Acid Sequence :

NPAQRDTHSL LPTHRRQKRD WIWNQMHIDE EKNTSLPHHV GKIKSSVSRK NAKYLLKGEY VGKVFRVDAE TGDVFAIERL DRENISEYHL TAVIVDKDTG ENLETPSSFT IKVHDVNDNW PVFTHRLFNA SVPESSAVGT SVISVTAVDA DDPTVGDHAS VMYQILKGKE YFAIDNSGRI ITITKSLDRE KQARYEIVVE ARDAQGLRGD SGTATVLVTL QDINDNFPFF TQTKYTFVVP EDTRVGTSVG SLFVEDPDEP QNRMTKYSIL RGDYQDAFTI ETNPAHNEGI IKPMKPLDYE YIQQYSFIVE ATDPTIDLRY MSPPAGNRAQ VIINITDVDE PPIFQQPFYH FQLKENQKKP LIGTVLAMDP DAARHSIGYS IRRTSDKGQF FRVTKKGDIY NEKELDREVY PWYNLTVEAK ELDSTGTPTG KESIVQVHIE VLDENDNAPE FAKPYQPKVC ENAVHGQLVL QISAIDKDIT PRNVKFKFIL NTENNFTLTD NHDNTANITV KYGQFDREHT KVHFLPVVIS DNGMPSRTGT STLTVAVCKC NEQGEFTFCE DMAAQVGVSI Q

Tag :

hIgG-His-Tag

Expression System :

Baculovirus

Predicted nterm :

Asn29

Product Type Name :

Recombinant Protein

UniProt No. :

P33151

Internal Search Terms :

VE-Cadherin, Cadherin-5, CDH5, 7B4, CD144,ATGP3506-10ug,ATGP3506-20ug,ATGP3506-50ug,ATGP3506-100ug,ATGP3506-250ug,ATGP3506-500ug,ATGP3506-1mg,ATGP3506-10,ATGP3506-20,ATGP3506-50,ATGP3506-100,ATGP3506-250,ATGP3506-500,ATGP3506-1

more info or order :

NKMAX product webpage