Recombinant human Kallikrein 5/KLK5 protein | NKMAX ATGP3501 product information

product summary

company name :

NKMAX

product type :

protein

product name :

Recombinant human Kallikrein 5/KLK5 protein

catalog :

ATGP3501

quantity :

10 ug

price :

80 USD

more info or order :

NKMAX product webpage

product information

Product Type :

Proteins

Item Name :

Recombinant human Kallikrein 5/KLK5 protein

Domain :

67-293aa

Catalog number (SKU) :

ATGP3501

NCBI :

NP_001070960

Description :

KLK5, also known as kallikrein-5, is one of the newly identified members of the kallikrein gene family, which is a subgroup of the serine protease enzyme family. It is highly expressed in skin, mammary gland and testis. KLK5 has been suggested to regulate cell shedding (desquamation) in conjunction with KLK7 and KLK14, given its ability to degrade proteins which form the extracellular component of cell junctions in the stratum corneum. It is proposed that KLK5 regulates this process since it is able to self-activate in addition to activating KLK7 and KLK14. Recombinant human KLK5, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.

Alternative Names :

Kallikrein-5, KLK5, KLKL2, SCTE, Kallikrein related peptidase 5, Kallikrein-like protein 2, Stratum corneum tryptic enzyme

Concentration :

0.5mg/ml (determined by absorbance at 280nm)

Formulation :

Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol

Storage :

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

General References :

Kim H., et al. (2001) Br J Cancer. 84:643-650.;; Pampalakis G., et al. (2014) Oncotarget. 5:2390-2403.

Purity :

> 95% by SDS-PAGE

Applications :

SDS-PAGE

Antigen Species :

Human

Gene Category :

Signal Transduction

Molecular Weight :

26.2 kDa (236aa)

Endotoxin :

< 1 EU per 1ug of protein (determined by LAL method)

Amino Acid Sequence :

ADLIINGSDC DMHTQPWQAA LLLRPNQLYC GAVLVHPQWL LTAAHCRKKV FRVRLGHYSL SPVYESGQQM FQGVKSIPHP GYSHPGHSND LMLIKLNRRI RPTKDVRPIN VSSHCPSAGT KCLVSGWGTT KSPQVHFPKV LQCLNISVLS QKRCEDAYPR QIDDTMFCAG DKAGRDSCQG DSGGPVVCNG SLQGLVSWGD YPCARPNRPG VYTNLCKFTK WIQETIQANS HHHHHH

Tag :

His-Tag

Expression System :

Baculovirus

Predicted nterm :

Ala

Product Type Name :

Recombinant Protein

UniProt No. :

Q9Y337

Internal Search Terms :

Kallikrein-5, KLK5, KLKL2, KLK-L2, SCTE, Kallikrein related peptidase 5, Kallikrein-like protein 2, Stratum corneum tryptic enzyme, ATGP3501-10ug, ATGP3501-20ug, ATGP3501-50ug, ATGP3501-100ug, ATGP3501-250ug, ATGP3501-500ug, ATGP3501-1mg, ATGP3501-010, ATGP3501-020, ATGP3501-050, ATGP3501-100, ATGP3501-250, ATGP3501-500, ATGP3501-01M

more info or order :

NKMAX product webpage