Recombinant mouse Cathepsin D protein | NKMAX ATGP3490 product information

product summary

company name :

NKMAX

product type :

protein

product name :

Recombinant mouse Cathepsin D protein

catalog :

ATGP3490

quantity :

5 ug

price :

105 USD

more info or order :

NKMAX product webpage

product information

Product Type :

Proteins

Item Name :

Recombinant mouse Cathepsin D protein

Domain :

21-410aa

Catalog number (SKU) :

ATGP3490

NCBI :

NP_034113

Description :

Ctsd, also known as cathepsin D, is peptidase belonging to the family of aspartic peptidases. It is intracellular catabolism in lysosomal compartments, other physiological effect include hormone and antigen processing. It plays an important role in alpha-synuclein degradation, and neuronal survival. It has also been shown to mediate apoptosis induced by various stimuli and p53-dependent tumor suppression. Recombinant mouse Ctsd, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.

Alternative Names :

Cathepsin D, Ctsd, CatD, CD

Concentration :

0.25mg/ml (determined by absorbance at 280nm)

Formulation :

Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol

Storage :

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

General References :

Crabtree D., et al. (2013) Neurosci Lett. 538:3-8.;; Tsukuba T., et al. (2000) Mol Cells. 10:601-611.

Purity :

> 90% by SDS-PAGE

Bioactivity Comment Only :

Specific activity is > 1,000pmol/min/ug in which one unit will convert 1.0pmole of Mca-PLGL-Dpa-AR-NH2 to MCA- Pro-Leu-OH per minute at pH 3.5 at 25C.

Applications :

Enzyme Activity,SDS-PAGE

Antigen Species :

Mouse

Gene Category :

Neuroscience

Molecular Weight :

44 kDa (398aa)

Endotoxin :

< 1 EU per 1ug of protein (determined by LAL method)

Bioactivity Comment and Pics :

Specific activity is > 1,000 pmol/min/ug in which one unit will convert 1.0 pmole of Mca-PLGL-Dpa-AR-NH2 to MCA- Pro-Leu-OH per minute at pH 3.5 at 25C.

Amino Acid Sequence :

IIRIPLRKFT SIRRTMTEVG GSVEDLILKG PITKYSMQSS PKTTEPVSEL LKNYLDAQYY GDIGIGTPPQ CFTVVFDTGS SNLWVPSIHC KILDIACWVH HKYNSDKSST YVKNGTSFDI HYGSGSLSGY LSQDTVSVPC KSDQSKARGI KVEKQIFGEA TKQPGIVFVA AKFDGILGMG YPHISVNNVL PVFDNLMQQK LVDKNIFSFY LNRDPEGQPG GELMLGGTDS KYYHGELSYL NVTRKAYWQV HMDQLEVGNE LTLCKGGCEA IVDTGTSLLV GPVEEVKELQ KAIGAVPLIQ GEYMIPCEKV SSLPTVYLKL GGKNYELHPD KYILKVSQGG KTICLSGFMG MDIPPPSGPL WILGDVFIGS YYTVFDRDNN RVGFANAVVL LEHHHHHH

Tag :

His-Tag

Expression System :

Baculovirus

Predicted nterm :

Ile21

Product Type Name :

Recombinant Protein

UniProt No. :

P18242

Internal Search Terms :

Cathepsin D, Cathepsin D, Ctsd, CatD, CD,ATGP3490-10ug,ATGP3490-20ug,ATGP3490-50ug,ATGP3490-100ug,ATGP3490-250ug,ATGP3490-500ug,ATGP3490-1mg,ATGP3490-10,ATGP3490-20,ATGP3490-50,ATGP3490-100,ATGP3490-250,ATGP3490-500,ATGP3490-1

more info or order :

NKMAX product webpage