Recombinant human t-Plasminogen Activator/PLAT protein | NKMAX ATGP3486 product information

product summary

company name :

NKMAX

product type :

protein

product name :

Recombinant human t-Plasminogen Activator/PLAT protein

catalog :

ATGP3486

quantity :

4 ug

price :

80 USD

more info or order :

NKMAX product webpage

product information

Product Type :

Proteins

Item Name :

Recombinant human t-Plasminogen Activator/PLAT protein

Domain :

24-562aa

Catalog number (SKU) :

ATGP3486

NCBI :

NP_000921

Description :

PLAT, as known as tissue-type plasminogen activator isoform 1, is a secreted serine protease synthesized by endothelial cells. This protein is secreted as a single chain polypeptide precursor which is cleaved in turn by plasmin. Also, it plays a role clinical medicine to treat stroke in cell migration and tissue remodeling. It is implicated in normal neural function and is suggested as a regulatory molecule in neurodegenerative diseases. Recombinant human PLAT, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.

Alternative Names :

Tissue-type plasminogen activator isoform 1, PLAT, T-PA, TPA

Concentration :

0.25mg/ml (determined by absorbance at 280nm)

Formulation :

Liquid in. 50mM MES buffer (pH 5.5) containing 40% glycerol, 5mM CaCl2, 1mM DTT, 0.5M NaCl

Storage :

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

General References :

Chevilley A., et al, (2015) Front Cell Neurosci. 9:415.;; Lansley SM., et al, (2015) Am. J. Respir. Cell Mol. Biol. 53:105-112.

Purity :

> 90% by SDS-PAGE

Applications :

SDS-PAGE

Antigen Species :

Human

Gene Category :

Cardiovascular

Molecular Weight :

61.3 kDa (545aa)

Endotoxin :

< 1 EU per 1ug of protein (determined by LAL method)

Amino Acid Sequence :

QEIHARFRRG ARSYQVICRD EKTQMIYQQH QSWLRPVLRS NRVEYCWCNS GRAQCHSVPV KSCSEPRCFN GGTCQQALYF SDFVCQCPEG FAGKCCEIDT RATCYEDQGI SYRGTWSTAE SGAECTNWNS SALAQKPYSG RRPDAIRLGL GNHNYCRNPD RDSKPWCYVF KAGKYSSEFC STPACSEGNS DCYFGNGSAY RGTHSLTESG ASCLPWNSMI LIGKVYTAQN PSAQALGLGK HNYCRNPDGD AKPWCHVLKN RRLTWEYCDV PSCSTCGLRQ YSQPQFRIKG GLFADIASHP WQAAIFAKHR RSPGERFLCG GILISSCWIL SAAHCFQERF PPHHLTVILG RTYRVVPGEE EQKFEVEKYI VHKEFDDDTY DNDIALLQLK SDSSRCAQES SVVRTVCLPP ADLQLPDWTE CELSGYGKHE ALSPFYSERL KEAHVRLYPS SRCTSQHLLN RTVTDNMLCA GDTRSGGPQA NLHDACQGDS GGPLVCLNDG RMTLVGIISW GLGCGQKDVP GVYTKVTNYL DWIRDNMRP

Tag :

His-Tag

Expression System :

Baculovirus

Predicted nterm :

Gln24

Product Type Name :

Recombinant Protein

UniProt No. :

P00750

Internal Search Terms :

t-Plasminogen Activator, Tpa, Tissue-type plasminogen activator isoform 1, PLAT, T-PA, TPA,ATGP3486-10ug,ATGP3486-20ug,ATGP3486-50ug,ATGP3486-100ug,ATGP3486-250ug,ATGP3486-500ug,ATGP3486-1mg,ATGP3486-10,ATGP3486-20,ATGP3486-50,ATGP3486-100,ATGP3486-250,ATGP3486-500,ATGP3486-1

more info or order :

NKMAX product webpage