product summary
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company name :
NKMAX
product type :
protein
product name :
Recombinant mouse FcRn/FCGRT protein
catalog :
ATGP3485
quantity :
10 ug
price :
105 USD
more info or order :
NKMAX product webpage
product information
Product Type :
Proteins
Item Name :
Recombinant mouse FcRn/FCGRT protein
Domain :
22-297aa
Catalog number (SKU) :
ATGP3485
NCBI :
NP_034319.2
Description :
Fcgrt, as known as IgG receptor FcRn large subunit p51, is a transmembrane glycoprotein with structural homology to MHC class 1 proteins. This protein is widely expressed in endothelial and epithelial cells and plays an important rloe in IgG homeostasis. Also, it is expessed in neutrophils and myeloid antigen presenting cells. It can enhance IgG-meditated phagocytosis and antigen presentation by heses cells, but it promotes the degradation of opsonizing IgG rather than returning it to the circulation. Recombinant mouse Fcgrt, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.
Alternative Names :
IgG receptor FcRn large subunit p51, Fcgrt, FcRn, Fc gamma receptor and transporter, FcgammaRn, Transmembrane alpha chain of the neonatal receptor, Neonatal Fc receptor, FCRN alpha-chai
Concentration :
0.5mg/ml (determined by absorbance at 280nm)
Formulation :
Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol
Storage :
Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
General References :
Baker K., et al, (2013) Immunity 39:1095-1107.;; Paveglio S., et al, (2012) Clin. Exp. Allergy 42:1791-1800.
Purity :
> 85% by SDS-PAGE
Applications :
SDS-PAGE
Antigen Species :
Mouse
Gene Category :
Immunology
Molecular Weight :
32.1 kDa (285aa)
Endotoxin :
< 1 EU per 1ug of protein (determined by LAL method)
Amino Acid Sequence :
SETRPPL MYHLTAVSNP STGLPSFWAT GWLGPQQYLT YNSLRQEADP CGAWMWENQV SWYWEKETTD LKSKEQLFLE ALKTLEKILN GTYTLQGLLG CELASDNSSV PTAVFALNGE EFMKFNPRIG NWTGEWPETE IVANLWMKQP DAARKESEFL LNSCPERLLG HLERGRRNLE WKEPPSMRLK ARPGNSGSSV LTCAAFSFYP PELKFRFLRN GLASGSGNCS TGPNGDGSFH AWSLLEVKRG DEHHYQCQVE HEGLAQPLTV DLDSSARSS
Tag :
His-Tag
Expression System :
Baculovirus
Predicted nterm :
Ala
Product Type Name :
Recombinant Protein
UniProt No. :
Q61559
Internal Search Terms :
IgG receptor FcRn large subunit p51, Fcgrt, FcRn, Fc gamma receptor and transporter, FcgammaRn, Transmembrane alpha chain of the neonatal receptor, Neonatal Fc receptor, FCRN alpha-chain, FCRN alpha chain, ATGP3485-10ug, ATGP3485-20ug, ATGP3485-50ug, ATGP3485-100ug, ATGP3485-250ug, ATGP3485-500ug, ATGP3485-1mg, ATGP3485-010, ATGP3485-020, ATGP3485-050, ATGP3485-100, ATGP3485-250, ATGP3485-500, ATGP3485-01M
more info or order :
NKMAX product webpage
company information
NKMAX
SNUH Health Care Innovation Park 6F
172 Dolma-ro, Bundang-gu
Seongnam-si, Gyeonggi-do
https://www.nkmaxbio.com
82-31-8017-8114
headquarters: South Korea
NKMAX Co. Ltd. is a biotech company that manufactures and supplies a unique line of quality proteins and antibodies worldwide to both researchers and retailers.