Recombinant human CRLF2 protein | NKMAX ATGP3478 product information

product summary

company name :

NKMAX

product type :

protein

product name :

Recombinant human CRLF2 protein

catalog :

ATGP3478

quantity :

10 ug

price :

80 USD

more info or order :

NKMAX product webpage

product information

Product Type :

Proteins

Item Name :

Recombinant human CRLF2 protein

Domain :

23-231aa

Catalog number (SKU) :

ATGP3478

NCBI :

NP_071431.2

Description :

CRLF2, also known as cytokine receptor-like factor 2 isoform 1, is a receptor for thymic stromal lymphopoietin. It is proposed to signal through a heterodimeric receptor complex that consists of a new member of the hemopoietin family termed CRLF2 and the IL-7R alpha-chain. The protein induces phosphorylation of Stat3 and Stat5 also activate JAK2 pathways. CRLF2 and IL-7R alpha are principally coexpressed on monocytes and dendritic cell populations and to a much lesser extent of various lymphoid cells. Recombinant human CRLF2, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.

Alternative Names :

Cytokine receptor-like factor 2 isoform 1 precursor, CRL2, CRLF2Y, TSLPR, Cytokine receptor-like factor 2 isoform 1, CRLF2, Cytokine receptor-like 2, ILXR, Thymic stromal lymphopoietin protein receptor, TSLP receptor

Concentration :

1mg/ml (determined by absorbance at 280nm)

Formulation :

Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol

Storage :

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

General References :

Reche PA., et al. (2001) J Immunol. 167:336-343.;; Chen IM., et al. (2012) Blood. 119:3512-3522.

Purity :

> 95% by SDS-PAGE

Applications :

SDS-PAGE

Antigen Species :

Human

Gene Category :

Immunology

Molecular Weight :

25.2 kDa (218aa)

Endotoxin :

< 1 EU per 1ug of protein (determined by LAL method)

Amino Acid Sequence :

QGGAAEG VQIQIIYFNL ETVQVTWNAS KYSRTNLTFH YRFNGDEAYD QCTNYLLQEG HTSGCLLDAE QRDDILYFSI RNGTHPVFTA SRWMVYYLKP SSPKHVRFSW HQDAVTVTCS DLSYGDLLYE VQYRSPFDTE WQSKQENTCN VTIEGLDAEK CYSFWVRVKA MEDVYGPDTY PSDWSEVTCW QRGEIRDACA ETPTPPKPKL SK

Tag :

His-Tag

Expression System :

Baculovirus

Predicted nterm :

Ala

Product Type Name :

Recombinant Protein

UniProt No. :

Q9HC73

Internal Search Terms :

TSLPR, TSLP R, Cytokine receptor-like factor 2 isoform 1 precursor, CRLF2Y, CRLF2, CRL2, ATGP3478-10ug, ATGP3478-20ug, ATGP3478-50ug, ATGP3478-100ug, ATGP3478-250ug, ATGP3478-500ug, ATGP3478-1mg, ATGP3478-010, ATGP3478-020, ATGP3478-050, ATGP3478-100, ATGP3478-250, ATGP3478-500, ATGP3478-01M

more info or order :

NKMAX product webpage