product summary
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company name :
NKMAX
product type :
protein
product name :
Recombinant mouse Carboxylesterase 3/CES3 protein
catalog :
ATGP3467
quantity :
10 ug
price :
160 USD
more info or order :
product information
Product Type :
Proteins
Item Name :
Recombinant mouse Carboxylesterase 3/CES3 protein
Domain :
19-565aa
Catalog number (SKU) :
ATGP3467
NCBI :
NP_444430
Description :
Ces1d, also known as carboxylesterase 1D, is a member of a large family of carboxylesterases that are responsible for the hydrolysis of ester and amide bonds. It is the principle lipase of white adipose tissue fat cake extracts. Partially purified white adipose tissue Ces1d had lipase activity as well as lesser but detectable neutral cholesteryl ester hydrolase activity. The protein shows low catalytic efficiency for hydrolysis of CPT-11, a prodrugs for camptothecin used in cancer therapeutics. Recombinant mouse Ces1d, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.
Alternative Names :
Carboxylesterase 1D, Ces1d, Ces3, TGH
Concentration :
0.5mg/ml (determined by absorbance at 280nm)
Formulation :
Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol
Storage :
Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
General References :
Soni KG., et al. (2004) J. Biol. Chem. 279:40683-40689.;; Sanghani SP., et al. (2004) Drug Metab Dispos. 32:505-511.
Purity :
> 90% by SDS-PAGE
Bioactivity Comment Only :
Specific activity is > 80,000pmol/min/ug and is defined as the amount of enzyme that hydrolyze 1pmole of p-nitrophenyl acetate to p-nitrophenol per minute at pH 7.5 at 37C
Applications :
SDS-PAGE, Enzyme Activity
Antigen Species :
Mouse
Gene Category :
Signal Transduction
Molecular Weight :
60.9 kDa (555aa)
Endotoxin :
< 1 EU per 1ug of protein (determined by LAL method)
Bioactivity Comment and Pics :
Specific activity is > 80,000 pmol/min/ug and is defined as the amount of enzyme that hydrolyze 1pmole of p-nitrophenyl acetate to p-nitrophenol per minute at pH 7.5 at 37C
Amino Acid Sequence :
YPSSPPVVNT VKGKVLGKYV NLEGFTQPVA VFLGVPFAKP PLGSLRFAPP QPAEPWSFVK NTTSYPPMCS QDAVGGQVLS ELFTNRKENI PLQFSEDCLY LNIYTPADLT KNSRLPVMVW IHGGGLVVGG ASTYDGLALS AHENVVVVTI QYRLGIWGFF STGDEHSRGN WGHLDQVAAL RWVQDNIANF GGNPGSVTIF GESAGGFSVS VLVLSPLAKN LFHRAISESG VSLTAALITT DVKPIAGLVA TLSGCKTTTS AVMVHCLRQK TEDELLETSL KLNLFKLDLL GNPKESYPFL PTVIDGVVLP KAPEEILAEK SFSTVPYIVG INKQEFGWII PTLMGYPLAE GKLDQKTANS LLWKSYPTLK ISENMIPVVA EKYLGGTDDL TKKKDLFQDL MADVVFGVPS VIVSRSHRDA GASTYMYEFE YRPSFVSAMR PKAVIGDHGD EIFSVFGSPF LKDGASEEET NLSKMVMKFW ANFARNGNPN GGGLPHWPEY DQKEGYLKIG ASTQAAQRLK DKEVSFWAEL RAKESAQRPS HREHVEL
Tag :
His-Tag
Expression System :
Baculovirus
Predicted nterm :
Tyr19
Product Type Name :
Recombinant Protein
UniProt No. :
Q8VCT4
Internal Search Terms :
Carboxylesterase3, CES3, Carboxylesterase 1D, Ces1d, Ces3, TGH,ATGP3467-10ug,ATGP3467-20ug,ATGP3467-50ug,ATGP3467-100ug,ATGP3467-250ug,ATGP3467-500ug,ATGP3467-1mg,ATGP3467-10,ATGP3467-20,ATGP3467-50,ATGP3467-100,ATGP3467-250,ATGP3467-500,ATGP3467-1
more info or order :
company information
NKMAX
SNUH Health Care Innovation Park 6F
172 Dolma-ro, Bundang-gu
Seongnam-si, Gyeonggi-do
https://www.nkmaxbio.com
82-31-8017-8114
headquarters: South Korea
NKMAX Co. Ltd. is a biotech company that manufactures and supplies a unique line of quality proteins and antibodies worldwide to both researchers and retailers.