Recombinant human TROP-2 protein | NKMAX ATGP3463 product information

product summary

company name :

NKMAX

product type :

protein

product name :

Recombinant human TROP-2 protein

catalog :

ATGP3463

quantity :

10 ug

price :

80 USD

more info or order :

NKMAX product webpage

product information

Product Type :

Proteins

Item Name :

Recombinant human TROP-2 protein

Domain :

31-274aa

Catalog number (SKU) :

ATGP3463

NCBI :

NP_002344.2

Description :

TACSTD2, also known as tumor-associated calcium signal transducer 2, is an identified cell surface glycoprotein highly expressed by human carcinomas. It is detected in normal kidney, lung, ovary and testis, similarly to the human gene. It is undetectable in undifferentiated spindle cell carcinomas, this suggests a preferential expression at early stages of tumor progression. Its inhibition suppresses the proliferation and invasion of laryngeal carcinoma cells via the extracellular signal-regulated kinase/mitogen-activated protein kinase pathway. Recombinant human TACSTD2, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.

Alternative Names :

Tumor-associated calcium signal transducer 2, TACSTD2, EGP-1, EGP1, GA733-1, GA7331, GP50, M1S1, TROP2

Concentration :

1mg/ml (determined by absorbance at 280nm)

Formulation :

Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol

Storage :

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

General References :

Wang XD., et al. (2015) Mol Med Rep. 12:865-870.;; Ripani E., et al. (1998) Int J Cancer. 76:671-676.

Purity :

> 95% by SDS-PAGE

Applications :

SDS-PAGE

Antigen Species :

Human

Gene Category :

Cancer

Molecular Weight :

28.6 kDa (253aa)

Endotoxin :

< 1 EU per 1ug of protein (determined by LAL method)

Amino Acid Sequence :

QDNCTCP TNKMTVCSPD GPGGRCQCRA LGSGMAVDCS TLTSKCLLLK ARMSAPKNAR TLVRPSEHAL VDNDGLYDPD CDPEGRFKAR QCNQTSVCWC VNSVGVRRTD KGDLSLRCDE LVRTHHILID LRHRPTAGAF NHSDLDAELR RLFRERYRLH PKFVAAVHYE QPTIQIELRQ NTSQKAAGDV DIGDAAYYFE RDIKGESLFQ GRGGLDLRVR GEPLQVERTL IYYLDEIPPK FSMKRLT

Tag :

His-Tag

Expression System :

Baculovirus

Predicted nterm :

Ala

Product Type Name :

Recombinant Protein

UniProt No. :

P09758

Internal Search Terms :

TROP2, Tumor-associated calcium signal transducer 2 , TACSTD2, EGP-1, EGP1, GA733-1, GA7331, GP50, M1S1, TROP2,ATGP3463-10ug,ATGP3463-20ug,ATGP3463-50ug,ATGP3463-100ug,ATGP3463-250ug,ATGP3463-500ug,ATGP3463-1mg,ATGP3463-10,ATGP3463-20,ATGP3463-50,ATGP3463-100,ATGP3463-250,ATGP3463-500,ATGP3463-1

more info or order :

NKMAX product webpage