Recombinant human Iduronate 2-Sulfatase protein | NKMAX ATGP3462 product information

product summary

company name :

NKMAX

product type :

protein

product name :

Recombinant human Iduronate 2-Sulfatase protein

catalog :

ATGP3462

quantity :

10 ug

price :

105 USD

more info or order :

NKMAX product webpage

product information

Product Type :

Proteins

Item Name :

Recombinant human Iduronate 2-Sulfatase protein

Domain :

26-550aa

Catalog number (SKU) :

ATGP3462

NCBI :

NP_000193

Description :

IDS, as known as iduronate 2-sulfatase isoform, is a member of the highly conserved sulfatase family of enzymes that catalyze the hydrolysis of O-sulfate and N-salfate esters from a varity of substrates. This protein is required for the lysosomal degradation of the glycosaminoglycans (GAG) heparan sulfate and dermatan sulfate. It hydrolyzes the 2-sulfate group of the IDS units of the GAG. Recombinant human IDS, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.

Alternative Names :

Iduronate 2-sulfatase isoform, IDS, MPS2, SIDS

Concentration :

0.25mg/ml (determined by absorbance at 280nm)

Formulation :

Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol

Storage :

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

General References :

Torres LC., et al, (2014) Clin. Immunol. 154:100-104.;; Chistiakov DA., et al, (2014) J. Genet. Genomics. 41:197-203.

Purity :

> 90% by SDS-PAGE

Applications :

SDS-PAGE

Antigen Species :

Human

Gene Category :

Enzymes & Proteases

Molecular Weight :

60.3 kDa (533aa)

Endotoxin :

< 1 EU per 1ug of protein (determined by LAL method)

Amino Acid Sequence :

SETQANSTTD ALNVLLIIVD DLRPSLGCYG DKLVRSPNID QLASHSLLFQ NAFAQQAVCA PSRVSFLTGR RPDTTRLYDF NSYWRVHAGN FSTIPQYFKE NGYVTMSVGK VFHPGISSNH TDDSPYSWSF PPYHPSSEKY ENTKTCRGPD GELHANLLCP VDVLDVPEGT LPDKQSTEQA IQLLEKMKTS ASPFFLAVGY HKPHIPFRYP KEFQKLYPLE NITLAPDPEV PDGLPPVAYN PWMDIRQRED VQALNISVPY GPIPVDFQRK IRQSYFASVS YLDTQVGRLL SALDDLQLAN STIIAFTSDH GWALGEHGEW AKYSNFDVAT HVPLIFYVPG RTASLPEAGE KLFPYLDPFD SASQLMEPGR QSMDLVELVS LFPTLAGLAG LQVPPRCPVP SFHVELCREG KNLLKHFRFR DLEEDPYLPG NPRELIAYSQ YPRPSDIPQW NSDKPSLKDI KIMGYSIRTI DYRYTVWVGF NPDEFLANFS DIHAGELYFV DSDPLQDHNM YNDSQGGDLF QLLMP

Tag :

His-Tag

Expression System :

Baculovirus

Predicted nterm :

Ser26

Product Type Name :

Recombinant Protein

UniProt No. :

P22304

Internal Search Terms :

Iduronate2-Sulfatase,ATGP3462-10ug,ATGP3462-20ug,ATGP3462-50ug,ATGP3462-100ug,ATGP3462-250ug,ATGP3462-500ug,ATGP3462-1mg,ATGP3462-10,ATGP3462-20,ATGP3462-50,ATGP3462-100,ATGP3462-250,ATGP3462-500,ATGP3462-1

more info or order :

NKMAX product webpage