Recombinant human IL-18BP protein | NKMAX ATGP3459 product information

product summary

company name :

NKMAX

product type :

protein

product name :

Recombinant human IL-18BP protein

catalog :

ATGP3459

quantity :

10 ug

price :

80 USD

more info or order :

NKMAX product webpage

product information

Product Type :

Proteins

Item Name :

Recombinant human IL-18BP protein

Domain :

31-194aa

Catalog number (SKU) :

ATGP3459

NCBI :

NP_001138529

Description :

IL18BP, as known as interleukin-18-binding protein isoform, is a secreted glycoprotein. It belongs to the interleukin 1 receptor family. This protein functions as an IL18 antagonist by binding to IL18 and blocking its biological activity. Also, it is essential for IL18 meditated signal transduction. The expression of IL18BP is markedly upregulated by IFN-gamma, suggesting that IL18 activity is modulated by a negative feedback mechanism meditated by IL18BP. Recombinant human IL18BP, fused to hIgG-His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.

Alternative Names :

Interleukin-18-binding protein, IL18BPa, Interleukin-18-binding protein isoform, IL18BP, Tadekinig-alfa

Concentration :

0.5mg/ml (determined by absorbance at 280nm)

Formulation :

Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol

Storage :

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

General References :

Wang YB., et al. (2011) J. Int. Med. Res. 39:2201-2208.;; Palladino I., et al, (2012) J Neuroinflammation 9:206.;;

Purity :

> 90% by SDS-PAGE

Applications :

SDS-PAGE

Antigen Species :

Human

Gene Category :

Immunology

Molecular Weight :

44.9 kDa (406aa)

Endotoxin :

< 1 EU per 1ug of protein (determined by LAL method)

Amino Acid Sequence :

TPVSQTT TAATASVRST KDPCPSQPPV FPAAKQCPAL EVTWPEVEVP LNGTLSLSCV ACSRFPNFSI LYWLGNGSFI EHLPGRLWEG STSRERGSTG TQLCKALVLE QLTPALHSTN FSCVLVDPEQ VVQRHVVLAQ LWAGLRATLP PTQEALPSSH SSPQQQG

Tag :

hIgG-His-Tag

Expression System :

Baculovirus

Predicted nterm :

Ala

Product Type Name :

Recombinant Protein

UniProt No. :

O95998

Internal Search Terms :

Interleukin-18 binding protein, Interleukin 18 binding protein, Interleukin-18-binding protein, IL18BPa, Interleukin 18 binding protein isoform, Interleukin-18-binding protein isoform, Interleukin18 binding protein isoform, IL18BP, Tadekinig-alfa, Tadekinig alfa, ATGP3459-10ug, ATGP3459-20ug, ATGP3459-50ug, ATGP3459-100ug, ATGP3459-250ug, ATGP3459-500ug, ATGP3459-1mg, ATGP3459-010, ATGP3459-020, ATGP3459-050, ATGP3459-100, ATGP3459-250, ATGP3459-500, ATGP3459-01M

more info or order :

NKMAX product webpage