product summary
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company name :
NKMAX
product type :
protein
product name :
Recombinant human ADAM10 protein
catalog :
ATGP3448
quantity :
10 ug
price :
240 USD
more info or order :
product information
Product Type :
Proteins
Item Name :
Recombinant human ADAM10 protein
Domain :
214-672aa
Catalog number (SKU) :
ATGP3448
NCBI :
NP_001101
Description :
ADAM10, as known as disintegrin and metalloproteinase domain-containing protein 10 isoform 1, is a member of the ADAM family that contains a disintegrin and metallogrotease-like domain. This protein is a sheddase, and has a broad specificity for peptide hydrolysis reactions. Also, it cleaves ephrin, within the ephrin/eph complex, formed between two cell surfaces. When ephrin is freed from the opposing cell, the entire ephrin/eph complex is endocytosed. In neurons, ADAM10 is the most important enzyme with alpha-secretase activity for proteolytic processing of the amyloid precursor protein. Recombinant human ADAM10, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.
Alternative Names :
Disintegrin and metalloproteinase domain-containing protein 10 isoform 1, ADAM10, AD10, AD18, CD156c, HsT18717, kuz, MADM, RAK
Concentration :
0.5mg/ml (determined by absorbance at 280nm)
Formulation :
Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol
Storage :
Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
General References :
Park GB., et al, (2015) Invest. Ophthalmol. Vis. Sci. 56:5162-5173.;; Zingoni A., et al, (2015) J. Immunol. 195:736-748.
Purity :
> 85% by SDS-PAGE
Applications :
SDS-PAGE
Antigen Species :
Human
Gene Category :
Apoptosis
Additional Comment Only :
N- terminal Sequence Analysis: Thr-Thr-Ser-Ala-Glu
Molecular Weight :
51.6 kDa (467aa)
Endotoxin :
< 1 EU per 1ug of protein (determined by LAL method)
Amino Acid Sequence :
TTSAEKNTCQ LYIQTDHLFF KYYGTREAVI AQISSHVKAI DTIYQTTDFS GIRNISFMVK RIRINTTADE KDPTNPFRFP NIGVEKFLEL NSEQNHDDYC LAYVFTDRDF DDGVLGLAWV GAPSGSSGGI CEKSKLYSDG KKKSLNTGII TVQNYGSHVP PKVSHITFAH EVGHNFGSPH DSGTECTPGE SKNLGQKENG NYIMYARATS GDKLNNNKFS LCSIRNISQV LEKKRNNCFV ESGQPICGNG MVEQGEECDC GYSDQCKDEC CFDANQPEGR KCKLKPGKQC SPSQGPCCTA QCAFKSKSEK CRDDSDCARE GICNGFTALC PASDPKPNFT DCNRHTQVCI NGQCAGSICE KYGLEECTCA SSDGKDDKEL CHVCCMKKMD PSTCASTGSV QWSRHFSGRT ITLQPGSPCN DFRGYCDVFM RCRLVDADGP LARLKKAIFS PELYENIAEL EHHHHHH
Tag :
His-Tag
Expression System :
Baculovirus
Product Type Name :
Recombinant Protein
UniProt No. :
O14672
Internal Search Terms :
ADAM10, Disintegrin and metalloproteinase domain-containing protein 10 isoform 1 , ADAM10, AD10, AD18, CD156c, HsT18717, kuz, MADM, RAK,ATGP3448-10ug,ATGP3448-20ug,ATGP3448-50ug,ATGP3448-100ug,ATGP3448-250ug,ATGP3448-500ug,ATGP3448-1mg,ATGP3448-10,ATGP3448-20,ATGP3448-50,ATGP3448-100,ATGP3448-250,ATGP3448-500,ATGP3448-1
more info or order :
company information
NKMAX
SNUH Health Care Innovation Park 6F
172 Dolma-ro, Bundang-gu
Seongnam-si, Gyeonggi-do
https://www.nkmaxbio.com172 Dolma-ro, Bundang-gu
Seongnam-si, Gyeonggi-do
82-31-8017-8114
headquarters: South Korea
NKMAX Co. Ltd. is a biotech company that manufactures and supplies a unique line of quality proteins and antibodies worldwide to both researchers and retailers.