product summary
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company name :
NKMAX
product type :
protein
product name :
Recombinant human TYRP1 protein
catalog :
ATGP3435
quantity :
10 ug
price :
240 USD
more info or order :
product information
Product Type :
Proteins
Item Name :
Recombinant human TYRP1 protein
Domain :
25-477aa
Catalog number (SKU) :
ATGP3435
NCBI :
NP_000541
Description :
TYRP1, also known as 5, 6-dihydroxyindole-2-carboxylic acid oxidase, is a melanosomal enzyme that belongs to the tyrosinase family and plays an important role in the melanin biosynthetic pathway. It is a melanocyte-specific gene product involved in eumelanin synthesis. It is involved in the oxidation of 5, 6-dihydroxyindole-2-carboxylic acid (DHICA) into indole-5, 6-quinone-2-carboxylic acid. It is regulated by the microphthalmia-associated transcription factor (MITF). Recombinant human TYRP1, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.
Alternative Names :
5, 6-dihydroxyindole-2-carboxylic acid oxidase, TYRP1, b-PROTEIN, CAS2, CATB, GP75, OCA3, TRP, TRP1, TYRP
Concentration :
0.25mg/ml (determined by absorbance at 280nm)
Formulation :
Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol
Storage :
Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
General References :
Sarangarajan R., et al. (2001) Pigment Cell Res. 14:437-444.;; Chalupa A., et al. (2015) J Invest Dermatol. 135:202-211.
Purity :
> 85% by SDS-PAGE
Applications :
SDS-PAGE
Antigen Species :
Human
Gene Category :
Cancer
Molecular Weight :
52.5 kDa (462aa)
Endotoxin :
< 1 EU per 1ug of protein (determined by LAL method)
Amino Acid Sequence :
QFPRQCA TVEALRSGMC CPDLSPVSGP GTDRCGSSSG RGRCEAVTAD SRPHSPQYPH DGRDDREVWP LRFFNRTCHC NGNFSGHNCG TCRPGWRGAA CDQRVLIVRR NLLDLSKEEK NHFVRALDMA KRTTHPLFVI ATRRSEEILG PDGNTPQFEN ISIYNYFVWT HYYSVKKTFL GVGQESFGEV DFSHEGPAFL TWHRYHLLRL EKDMQEMLQE PSFSLPYWNF ATGKNVCDIC TDDLMGSRSN FDSTLISPNS VFSQWRVVCD SLEDYDTLGT LCNSTEDGPI RRNPAGNVAR PMVQRLPEPQ DVAQCLEVGL FDTPPFYSNS TNSFRNTVEG YSDPTGKYDP AVRSLHNLAH LFLNGTGGQT HLSPNDPIFV LLHTFTDAVF DEWLRRYNAD ISTFPLENAP IGHNRQYNMV PFWPPVTNTE MFVTAPDNLG YTYEIQWPSR EFSVPE
Tag :
His-Tag
Expression System :
Baculovirus
Predicted nterm :
Ala
Product Type Name :
Recombinant Protein
UniProt No. :
P17643
Internal Search Terms :
TYRP1,ATGP3435-10ug,ATGP3435-20ug,ATGP3435-50ug,ATGP3435-100ug,ATGP3435-250ug,ATGP3435-500ug,ATGP3435-1mg,ATGP3435-10,ATGP3435-20,ATGP3435-50,ATGP3435-100,ATGP3435-250,ATGP3435-500,ATGP3435-1
more info or order :
company information
NKMAX
SNUH Health Care Innovation Park 6F
172 Dolma-ro, Bundang-gu
Seongnam-si, Gyeonggi-do
https://www.nkmaxbio.com172 Dolma-ro, Bundang-gu
Seongnam-si, Gyeonggi-do
82-31-8017-8114
headquarters: South Korea
NKMAX Co. Ltd. is a biotech company that manufactures and supplies a unique line of quality proteins and antibodies worldwide to both researchers and retailers.