Recombinant human IL-4 protein | NKMAX ATGP3421 product information

product summary

company name :

NKMAX

product type :

protein

product name :

Recombinant human IL-4 protein

catalog :

ATGP3421

quantity :

10 ug

price :

105 USD

more info or order :

NKMAX product webpage

product information

Product Type :

Proteins

Item Name :

Recombinant human IL-4 protein

Domain :

25-153aa

Catalog number (SKU) :

ATGP3421

NCBI :

NP_000580.1

Description :

IL4, also known as Interleukin 4 isoform1, is a pleiotropic cytokine that has many biological roles, including the stimulation of activated B-cell and T-cell proliferation, and the differentiation of naive helper T-cell to Th2 cells. IL4 is a co-stimulator of DNA-synthesis and is induces the expression of class II MHC molecules on resting B-cells. It also enhances both secretion and cell surface expression of IgE and IgG1. Recombinant human IL4, was expressed in E. coli and purified by using conventional chromatography techniques.

Alternative Names :

Pitrakinra, MGC79402, Lymphocyte stimulatory factor 1, Interleukin-4 isoform 1, Interleukin 4, IL-4, BSF1, Binetrakin, BCGF1, B-cell stimulatory factor 1, B-cell growth factor 1, BCDF

Concentration :

1mg/ml (determined by BCA assay)

Formulation :

Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol

Storage :

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

General References :

Van Kimmenade A., et al (1988). Eur J Biochem. 173(1): 109-14;; Yokota T., et al (1986). Proc. Nati. Acad. Sci. USA. 83(16): 5894-8;;

Purity :

> 95% by SDS-PAGE

Bioactivity Comment Only :

Measured in a cell proliferation assay using TF-1 human erythroleukemic cells. The ED50 range ≤0.6ng/ml.

Applications :

SDS-PAGE, Bioactivity

Antigen Species :

Human

Gene Category :

Hormones & Cytokines

Molecular Weight :

15 kDa (130aa)

Endotoxin :

< 1 EU per 1ug of protein (determined by LAL method)

Bioactivity Comment and Pics :

Human IL-4 stimulates cell proliferation of the TF-1 human erythroleukemic cells. The ED50 range ≤0.6 ng/ml.

Amino Acid Sequence :

MHKCDITLQE IIKTLNSLTE QKTLCTELTV TDIFAASKNT TEKETFCRAA TVLRQFYSHH EKDTRCLGAT AQQFHRHKQL IRFLKRLDRN LWGLAGLNSC PVKEANQSTL ENFLERLKTI MREKYSKCSS

Tag :

Non-Tagged

Expression System :

E.coli

Product Type Name :

Recombinant Protein

UniProt No. :

P05112

Internal Search Terms :

Pitrakinra, Pitrakinara, MGC79402, Lymphocyte stimulatory factor 1, Interleukin-4 isoform 1, Interleukin-4, Interleukin4, Interleukin 4 isoform 1, Interleukin 4, IL-4, IL4, IL 4, BSF-1, BSF1, BSF 1, Binetrakin, BCGF-1, BCGF1, BCGF 1, B-cell stimulatory factor 1, B-cell growth factor 1, BCDF, B cell stimulatory factor 1, B cell growth factor 1, ATGP3421-10ug, ATGP3421-20ug, ATGP3421-50ug, ATGP3421-100ug, ATGP3421-250ug, ATGP3421-500ug, ATGP3421-1mg, ATGP3421-010, ATGP3421-020, ATGP3421-050, ATGP3421-100, ATGP3421-250, ATGP3421-500, ATGP3421-01M

more info or order :

NKMAX product webpage