Recombinant human TNFRSF7/CD27 protein | NKMAX ATGP3416 product information

product summary

company name :

NKMAX

product type :

protein

product name :

Recombinant human TNFRSF7/CD27 protein

catalog :

ATGP3416

quantity :

10 ug

price :

77 USD

more info or order :

NKMAX product webpage

product information

Product Type :

Proteins

Item Name :

Recombinant human TNFRSF7/CD27 protein

Domain :

21-191aa

Catalog number (SKU) :

ATGP3416

NCBI :

NP_001233.1

Description :

CD27, as known as CD27 antigen, is a member of the TNF-receptor superfamily limited to cells of the lymphoid lineage, and exists as both a dimeric glycosylation on the cell surface and as a soluble protein in serum. As a T and B cell co-stimulatory molecule, the activity of CD27 is governed by its TNF-like ligand CD 70 on lymphocytes and dendritic cells. This protein plays a key role in regulating B-cell differentiation, activation and immunoglobulin synthesis. Recombinant human CD27, fused to hIgG-His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.

Alternative Names :

CD27L receptor, T-cell activation antigen CD27, T14, Tumor necrosis factor receptor superfamily member 7, TNFRSF7, T cell antivation antigen S152, TP55

Concentration :

0.5mg/ml (determined by absorbance at 280nm)

Formulation :

Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol

Storage :

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

General References :

Clemente A., et al. (2013) Clin. Exp. Immunol. 174:97-108.;; Huang J., et al. (2013) J. Immunol. 190:6250-6258.

Purity :

> 85% by SDS-PAGE

Bioactivity Comment Only :

Measured by its binding ability in a functional ELISA with Human CD27 Ligand/TNFSF7 (CAT# ATGP3336). The ED50 range ≤ 0.5 ug/ml.

Applications :

SDS-PAGE, Bioactivity

Antigen Species :

Human

Gene Category :

Immunology

Molecular Weight :

46.4 kDa (413aa)

Endotoxin :

< 1 EU per 1ug of protein (determined by LAL method)

Bioactivity Comment and Pics :

Human CD27 Ligand/TNFSF7 (CAT# ATGP3336) is coated at 10 ug/ml (100 ul/well) can bind Human CD27/TNFRSF7. The ED50 range ≤ 0.5 ug/ml.

Amino Acid Sequence :

TPAPKSC PERHYWAQGK LCCQMCEPGT FLVKDCDQHR KAAQCDPCIP GVSFSPDHHT RPHCESCRHC NSGLLVRNCT ITANAECACR NGWQCRDKEC TECDPLPNPS LTARSSQALS PHPQPTHLPY VSEMLEARTA GHMQTLADFR QLPARTLSTH WPPQRSLCSS DFIR

Tag :

hIgG-His-Tag

Expression System :

Baculovirus

Predicted nterm :

Ala

Product Type Name :

Recombinant Protein

UniProt No. :

P26842

Internal Search Terms :

CD27, TNFRSF7, CD27 antigen, CD27, S152, LPFS2, T14, TNFRSF7, Tp55, CD 27, CD27 antigen, CD27 molecule, CD27_HUMAN, CD27L receptor, LPFS2, MGC20393, OTTHUMP00000238557, S152, T cell activation antigen CD27, T cell antivation antigen S152, T-cell activation antigen CD27, T14, TNFRSF 7, TNFRSF7, TNFSF7, Tp 55,Tp55, Tumor necrosis factor receptor superfamily member 7,ATGP3416-10ug,ATGP3416-20ug,ATGP3416-50ug,ATGP3416-100ug,ATGP3416-250ug,ATGP3416-500ug,ATGP3416-1mg,ATGP3416-10,ATGP3416-20,ATGP3416-50,ATGP3416-100,ATGP3416-250,ATGP3416-500,ATGP3416-1

more info or order :

NKMAX product webpage