Recombinant human TIMP-4 protein | NKMAX ATGP3407 product information

product summary

company name :

NKMAX

product type :

protein

product name :

Recombinant human TIMP-4 protein

catalog :

ATGP3407

quantity :

10 ug

price :

240 USD

more info or order :

NKMAX product webpage

product information

Product Type :

Proteins

Item Name :

Recombinant human TIMP-4 protein

Domain :

30-224aa

Catalog number (SKU) :

ATGP3407

NCBI :

NP_003247

Description :

TIMP4, as known as metalloproteinase inhibitor 4, is a family of secreted protein that regulates the activation and proteolytic activity of the zinc enzymes known as matrix metalloproteinases. There are four known members of the family, TIMP1, 2, 3 and 4. TIMP4 is produced by a wide range of tissues, particularly brain, heart, ovary and skeletal muscle. Limited studies have shown that this protein has a tumor suppressive effect against Wilm s tumor, exhibits negative correlation with glioma malignancy and is found in breast carcinoma cells. Recombinant human TIMP4, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.

Alternative Names :

Metalloproteinase inhibitor 4, TIMP4, TIMP-4, Metalloproteinase inhibitor 4, TIMP 4, TIMP metallopeptidase inhibitor 4, TIMP-4, Timp4, TIMP4_HUMAN, Tissue inhibitor of metalloproteinase 4, Tissue inhibitor of metalloproteinases 4

Concentration :

0.25mg/ml (determined by absorbance at 280nm)

Formulation :

Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol

Storage :

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

General References :

Greene J., et al. (1996) J Biol Chem. 271:30375-80.;; Groft LL., et al. (2001) Br J Cancer. 85:55-63.;;

Purity :

> 90% by SDS-PAGE

Applications :

SDS-PAGE

Antigen Species :

Human

Gene Category :

Cardiovascular

Molecular Weight :

23.5 kDa (204aa)

Endotoxin :

< 1 EU per 1ug of protein (determined by LAL method)

Amino Acid Sequence :

CSCAPAH PQQHICHSAL VIRAKISSEK VVPASADPAD TEKMLRYEIK QIKMFKGFEK VKDVQYIYTP FDSSLCGVKL EANSQKQYLL TGQVLSDGKV FIHLCNYIEP WEDLSLVQRE SLNHHYHLNC GCQITTCYTV PCTISAPNEC LWTDWLLERK LYGYQAQHYV CMKHVDGTCS WYRGHLPLRK EFVDIVQP

Tag :

His-Tag

Expression System :

Baculovirus

Predicted nterm :

Ala

Product Type Name :

Recombinant Protein

UniProt No. :

Q99727

Internal Search Terms :

TIMP4, Metalloproteinase inhibitor 4 , TIMP4, TIMP-4, Metalloproteinase inhibitor 4TIMP 4, TIMP metallopeptidase inhibitor 4TIMP-4, Timp4, TIMP4_HUMANTissue inhibitor of metalloproteinase 4Tissue inhibitor of metalloproteinases 4,ATGP3407-10ug,ATGP3407-20ug,ATGP3407-50ug,ATGP3407-100ug,ATGP3407-250ug,ATGP3407-500ug,ATGP3407-1mg,ATGP3407-10,ATGP3407-20,ATGP3407-50,ATGP3407-100,ATGP3407-250,ATGP3407-500,ATGP3407-1

more info or order :

NKMAX product webpage