Recombinant mouse IL-1 beta/IL1B protein | NKMAX ATGP3398 product information

product summary

company name :

NKMAX

product type :

protein

product name :

Recombinant mouse IL-1 beta/IL1B protein

catalog :

ATGP3398

quantity :

10 ug

price :

130 USD

more info or order :

NKMAX product webpage

product information

Product Type :

Proteins

Item Name :

Recombinant mouse IL-1 beta/IL1B protein

Domain :

118-269aa

Catalog number (SKU) :

ATGP3398

NCBI :

NP_032387

Description :

IL-1beta is an inflammatory cytokine that might modulate angiogenesis by directly interacting with vascular endothelial cells or enhancing the production of proangiogenic factors via paracrine control. IL-1beta stimulates endothelial cell migration and proliferation, adhesion-molecule expression, inflammatory mediator production, and leukocyte recruitment. IL-1beta is required for tumor growth, metastasis, and angiogenesis in several animal models. Recombinant mouse IL-1beta, fused to His tag, was expressed in E. coli and purified by using conventional chromatography techniques.

Alternative Names :

Interleukin-1 beta, IL-1 beta

Concentration :

1mg/ml (determined by Bradford assay)

Formulation :

Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 10% glycerol

Storage :

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

General References :

Saijo Y, et al, (2002) J. Immunol. 169:469-475.;; Torisu H, et al, (2000) J. Cancer. 85:182-188.;;

Purity :

> 90% by SDS-PAGE

Bioactivity Comment Only :

Measured in a cell proliferation assay using D10.G4.1 mouse helper T cells. The ED50 range ≤0.1ng/ml.

Applications :

SDS-PAGE, Bioactivity

Antigen Species :

Mouse

Gene Category :

Hormones & Cytokines

Molecular Weight :

21 kDa (189aa) confirmed by MALDI-TOF

Endotoxin :

< 1 EU per 1ug of protein (determined by LAL method)

Bioactivity Comment and Pics :

Mouse IL-1 beta /IL-1F2 stimulates cell proliferation of the D10.G4.1 mouse helper T cells. The ED50 range ≤0.1 ng/ml.

Amino Acid Sequence :

MVPI RQLHYRLRDE QQKSLVLSDP YELKALHLNG QNINQQVIFS MSFVQGEPSN DKIPVALGLK GKNLYLSCVM KDGTPTLQLE SVDPKQYPKK KMEKRFVFNK IEVKSKVEFE SAEFPNWYIS TSQAEHKPVF LGNNSGQDII DFTMESVSS

Tag :

His-Tag

Expression System :

E.coli

Product Type Name :

Recombinant Protein

UniProt No. :

P10749

Internal Search Terms :

Pro interleukin 1 beta, Preinterleukin beta, Preinterleukin 1 beta, OTTHUMP00000162031, Osteoclast activating factor, OAF, Mouse IL1 beta, LAF, Interleukin-1 beta, Interleukin 1 beta precursor, Interleukin 1 beta Catabolin, Interleukin 1 beta, IL1F2, IL-1beta, IL1B_HUMAN, IL-1b, IL1B, IL1 F2, IL-1 beta, IL1 BETA, IL1 b, IL 1B, IL 1 beta, IL 1, IFN beta inducing factor, Hematopoietin 1, H1, Catabolin, ATGP3398-10ug, ATGP3398-20ug, ATGP3398-50ug, ATGP3398-100ug, ATGP3398-250ug, ATGP3398-500ug, ATGP3398-1mg, ATGP3398-010, ATGP3398-020, ATGP3398-050, ATGP3398-100, ATGP3398-250, ATGP3398-500, ATGP3398-01M

more info or order :

NKMAX product webpage