Recombinant human Pepsinogen C/PGC protein | NKMAX ATGP3385 product information

product summary

company name :

NKMAX

product type :

protein

product name :

Recombinant human Pepsinogen C/PGC protein

catalog :

ATGP3385

quantity :

4 ug

price :

80 USD

more info or order :

NKMAX product webpage

product information

Product Type :

Proteins

Item Name :

Recombinant human Pepsinogen C/PGC protein

Domain :

17-388aa

Catalog number (SKU) :

ATGP3385

NCBI :

NP_002621

Description :

PGC, also known as gastricsin, is an aspartic proteinase that belongs to the peptidase family A1. It is synthesized in the gastric mucosa as inactive precursors. It contains a prosegment that serves to stabilize the inactive form and prevent entry of the substrate to the active site. Serum levels of PGC are used as a biomarker for certain gastric diseases including Helicobacter pylori related gastritis. Recombinant human PGC, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques

Alternative Names :

Gastricsin, PGC, PEPC, PGII, Gastricsin, PEPC_HUMAN, pepsin C, Pepsinogen C, pepsinogen group II, PGII, preprogastricsin, Progastricsin

Concentration :

0.25mg/ml (determined by absorbance at 280nm)

Formulation :

Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol

Storage :

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

General References :

Richter C., et al. (1998) Biochem J. 335:481-490.;; Westerveld BD., et al. (1987) Gastroenterology. 93:774-778.

Purity :

> 95% by SDS-PAGE

Applications :

SDS-PAGE

Antigen Species :

Human

Gene Category :

Epigenomics (Transcription & Translation)

Molecular Weight :

41.6 kDa (380aa)

Endotoxin :

< 1 EU per 1ug of protein (determined by LAL method)

Amino Acid Sequence :

AVVKVPLKKF KSIRETMKEK GLLGEFLRTH KYDPAWKYRF GDLSVTYEPM AYMDAAYFGE ISIGTPPQNF LVLFDTGSSN LWVPSVYCQS QACTSHSRFN PSESSTYSTN GQTFSLQYGS GSLTGFFGYD TLTVQSIQVP NQEFGLSENE PGTNFVYAQF DGIMGLAYPA LSVDEATTAM QGMVQEGALT SPVFSVYLSN QQGSSGGAVV FGGVDSSLYT GQIYWAPVTQ ELYWQIGIEE FLIGGQASGW CSEGCQAIVD TGTSLLTVPQ QYMSALLQAT GAQEDEYGQF LVNCNSIQNL PSLTFIINGV EFPLPPSSYI LSNNGYCTVG VEPTYLSSQN GQPLWILGDV FLRSYYSVYD LGNNRVGFAT AA

Tag :

His-Tag

Expression System :

Baculovirus

Predicted nterm :

Ala17

Product Type Name :

Recombinant Protein

UniProt No. :

P20142

Internal Search Terms :

Pepsinogen PGC, Gastricsin, PGC, PEPC, PGII, Gastricsin, PEPC_HUMAN, pepsin C, Pepsinogen C, pepsinogen group II, PGII, preprogastricsin, Progastricsin,ATGP3385-10ug,ATGP3385-20ug,ATGP3385-50ug,ATGP3385-100ug,ATGP3385-250ug,ATGP3385-500ug,ATGP3385-1mg,ATGP3385-10,ATGP3385-20,ATGP3385-50,ATGP3385-100,ATGP3385-250,ATGP3385-500,ATGP3385-1

more info or order :

NKMAX product webpage