This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
NKMAX
product type :
protein
product name :
Recombinant human Noggin protein
catalog :
ATGP3369
quantity :
10 ug
price :
130 USD
product information
Product Type :
Proteins
Item Name :
Recombinant human Noggin protein
Domain :
28-232aa
Catalog number (SKU) :
ATGP3369
NCBI :
NP_005441
Description :
NOG, also known as noggin, is a secreted protein involved at multiple stages of vertebrate embryonic development including neural induction and is known to exert its effects by inhibiting the bone morphogenetic protein (BMP) -signaling pathway. It binds several BMPs with very high affinities, with a marked preference for BMP2 and BMP4 over BMP7. It plays a key role in neural induction by inhibiting BMP4, along with other TGF-beta signaling inhibitors such as chordin and follistatin. Recombinant human NOG, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.
Alternative Names :
Noggin, NOG, SYM1, SYNS1, SYNS1A
Concentration :
0.25mg/ml (determined by absorbance at 280nm)
Formulation :
Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol
Storage :
Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
General References :
Zimmerman LB., et al. (1996) Cell. 86:599-606. ;; Groppe J., et al. (2002) Nature. 420:636-642.
Purity :
> 90% by SDS-PAGE
Applications :
SDS-PAGE
Antigen Species :
Human
Gene Category :
Stem Cell
Molecular Weight :
23.8 kDa (211aa)
Endotoxin :
< 1 EU per 1ug of protein (determined by LAL method)
Bioassay Procedure :
QHYLHIRPAP SDNLPLVDLI EHPDPIFDPK EKDLNETLLR SLLGGHYDPG FMATSPPEDR PGGGGGAAGG AEDLAELDQL LRQRPSGAMP SEIKGLEFSE GLAQGKKQRL SKKLRRKLQM WLWSQTFCPV LYAWNDLGSR FWPRYVKVGS CFSKRSCSVP EGMVCKPSKS VHLTVLRWRC QRRGGQRCGW IPIQYPIISE CKCSCHHHHH H
Tag :
His-Tag
Expression System :
Baculovirus
Predicted nterm :
Gln28
Product Type Name :
Recombinant Protein
UniProt No. :
Q13253
Internal Search Terms :
Noggin, Noggin , NOG, SYM1, SYNS1, SYNS1A
Size 1 :
10 ug
Price 1 (USD) :
130 USD
company information
NKMAX
SNUH Health Care Innovation Park 6F
172 Dolma-ro, Bundang-gu
Seongnam-si, Gyeonggi-do
salesbio@atgenglobal.com
http://www.atgenglobal.com
82-31-8017-8114
headquarters: South Korea
NKMAX Co. Ltd. is a biotech company that manufactures and supplies a unique line of quality proteins and antibodies worldwide to both researchers and retailers.