product summary
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company name :
NKMAX
product type :
protein
product name :
Recombinant mouse Endoglin/CD105 protein
catalog :
ATGP3361
quantity :
10 ug
price :
150 USD
more info or order :
product information
Product Type :
Proteins
Item Name :
Recombinant mouse Endoglin/CD105 protein
Domain :
27-581aa
Catalog number (SKU) :
ATGP3361
NCBI :
NP_031958
Description :
Eng, also known as endoglin, is a type I homodimeric transmembrane glycoprotein with a large, disulfide-linked, extracellular region and a short, constitutively phosphorylated cytoplasmic tail. It is highly expressed on vascular endothelial cells, chondrocytes, and syncytiotrophoblasts of term placenta. It is also found on activated monocytes, mesenchymal stem cells and leukemic cells of lymphoid and myeloid lineages. Recombinant mouse Eng, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.
Alternative Names :
AI528660, AI662476, CD105, Cell surface MJ7/18 antigen, Endo, Endoglin, Eng, ORW, ORW1, Osler-Rendu-Weber syndrome 1, S-endoglin
Concentration :
0.5mg/ml (determined by absorbance at 280nm)
Formulation :
Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol
Storage :
Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
General References :
Ten Dijke P., et al. (2008) Angiogenesis. 11:79-89.;; Bernabeu C., et al. (2007) J Cell Biochem. 102:1375-1388.
Purity :
> 95% by SDS-PAGE
Bioactivity Comment Only :
Measured by its binding ability in a functional ELISA with Human TGF-beta RI (CAT# ATGP4134).
Applications :
SDS-PAGE, Bioactivity
Antigen Species :
Mouse
Gene Category :
Immunology
Molecular Weight :
60.9 kDa (563aa)
Endotoxin :
< 1 EU per 1ug of protein (determined by LAL method)
Bioactivity Comment and Pics :
Mouse Endoglin (CAT# ATGP3361) is coated at 10 ug/ml (100 ul/well) can bind Human TGF-beta RI (CAT# ATGP4134) in a Functional ELISA assay.
Amino Acid Sequence :
ERVGCDLQPV DPTRGEVTFT TSQVSEGCVA QAANAVREVH VLFLDFPGML SHLELTLQAS KQNGTETQEV FLVLVSNKNV FVKFQAPEIP LHLAYDSSLV IFQGQPRVNI TVLPSLTSRK QILDWAATKG AITSIAALDD PQSIVLQLGQ DPKAPFLCLP EAHKDMGATL EWQPRAQTPV QSCRLEGVSG HKEAYILRIL PGSEAGPRTV TVMMELSCTS GDAILILHGP PYVSWFIDIN HSMQILTTGE YSVKIFPGSK VKGVELPDTP QGLIAEARKL NASIVTSFVE LPLVSNVSLR ASSCGGVFQT TPAPVVTTPP KDTCSPVLLM SLIQPKCGNQ VMTLALNKKH VQTLQCTITG LTFWDSSCQA EDTDDHLVLS SAYSSCGMKV TAHVVSNEVI ISFPSGSPPL RKKVQCIDMD SLSFQLGLYL SPHFLQASNT IELGQQAFVQ VSVSPLTSEV TVQLDSCHLD LGPEGDMVEL IQSRTAKGSC VTLLSPSPEG DPRFSFLLRV YMVPTPTAGT LSCNLALRPS TLSQEVYKTV SMRLNIVSPD LSGKG
Tag :
His-Tag
Expression System :
Baculovirus
Predicted nterm :
Glu27
Product Type Name :
Recombinant Protein
UniProt No. :
Q63961
Internal Search Terms :
AI528660, AI662476, CD 105, CD105, CD-105, Cell surface MJ7/18 antigen, Endo, Endoglin, Eng, ORW, ORW 1, ORW1, Osler Rendu Weber syndrome 1, Osler-Rendu-Weber syndrome 1, S endoglin, S-endoglin, ATGP3361-10ug, ATGP3361-20ug, ATGP3361-50ug, ATGP3361-100ug, ATGP3361-250ug, ATGP3361-500ug, ATGP3361-1mg, ATGP3361-010, ATGP3361-020, ATGP3361-050, ATGP3361-100, ATGP3361-250, ATGP3361-500, ATGP3361-01M
more info or order :
company information
NKMAX
SNUH Health Care Innovation Park 6F
172 Dolma-ro, Bundang-gu
Seongnam-si, Gyeonggi-do
https://www.nkmaxbio.com172 Dolma-ro, Bundang-gu
Seongnam-si, Gyeonggi-do
82-31-8017-8114
headquarters: South Korea
NKMAX Co. Ltd. is a biotech company that manufactures and supplies a unique line of quality proteins and antibodies worldwide to both researchers and retailers.