product summary
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company name :
NKMAX
product type :
protein
product name :
Recombinant mouse B7-1/CD80 protein
catalog :
ATGP3353
quantity :
10 ug
price :
61 USD
more info or order :
NKMAX product webpage
product information
Product Type :
Proteins
Item Name :
Recombinant mouse B7-1/CD80 protein
Domain :
37-246aa
Catalog number (SKU) :
ATGP3353
NCBI :
NP_033985
Description :
Cd80, also known as T-lymphocyte activation antigen CD80, is a member of cell surface immunoglobulin superfamily and is expressed on the surface of antigen-presenting cells including activated B cells, macrophages and dendritic cells. It is the ligand for two different proteins on the T cell surface: Cd28 (for autoregulation and intercellular association) and Ctla4 (for attenuation of regulation and cellular disassociation). This protein also plays a role in induction of innate immune responses by activating NF-KB-signaling pathway in macrophages. It is thus regarded as promising therapeutic targets for autoimmune diseases and various carcinomas. Recombinant mouse Cd80, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.
Alternative Names :
T-lymphocyte activation antigen CD80, Cd80, Cd28l, Ly-53, Ly53, MIC17, TSA1, Activation B7-1 antigen, B7
Concentration :
0.25mg/ml (determined by absorbance at 280nm)
Formulation :
Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol
Storage :
Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
General References :
Peach R., et al. (1995) J. Biol. Chem. 270: 21181-21187.;; Suvas S., et al. (2002) J. Biol. Chem. 277:7766-7775.
Purity :
> 95% by SDS-PAGE
Bioactivity Comment Only :
Measured by its binding ability in a functional ELISA with Mouse CTLA4 (CAT# ATGP4046).
Applications :
SDS-PAGE, Bioactivity
Antigen Species :
Mouse
Gene Category :
Immunology
Molecular Weight :
24.7 kDa (216aa)
Endotoxin :
< 1 EU per 1ug of protein (determined by LAL method)
Bioactivity Comment and Pics :
Mouse CD80 is coated at 2 ug/ml (100 ul/well) can bind Mouse CTLA4 (CAT# ATGP4046) in a Functional ELISA assay.
Amino Acid Sequence :
DVDEQLSKSV KDKVLLPCRY NSPHEDESED RIYWQKHDKV VLSVIAGKLK VWPEYKNRTL YDNTTYSLII LGLVLSDRGT YSCVVQKKER GTYEVKHLAL VKLSIKADFS TPNITESGNP SADTKRITCF ASGGFPKPRF SWLENGRELP GINTTISQDP ESELYTISSQ LDFNTTRNHT IKCLIKYGDA HVSEDFTWEK PPEDPPDSKN
Tag :
His-Tag
Expression System :
Baculovirus
Predicted nterm :
Gln37
Product Type Name :
Recombinant Protein
UniProt No. :
Q00609
Internal Search Terms :
B71, CD80, T-lymphocyte activation antigen CD80, Cd80, Cd28l, Ly-53, Ly53, MIC17, TSA1,ATGP3353-10ug,ATGP3353-20ug,ATGP3353-50ug,ATGP3353-100ug,ATGP3353-250ug,ATGP3353-500ug,ATGP3353-1mg,ATGP3353-10,ATGP3353-20,ATGP3353-50,ATGP3353-100,ATGP3353-250,ATGP3353-500,ATGP3353-1
more info or order :
NKMAX product webpage
company information
NKMAX
SNUH Health Care Innovation Park 6F
172 Dolma-ro, Bundang-gu
Seongnam-si, Gyeonggi-do
https://www.nkmaxbio.com
82-31-8017-8114
headquarters: South Korea
NKMAX Co. Ltd. is a biotech company that manufactures and supplies a unique line of quality proteins and antibodies worldwide to both researchers and retailers.