Recombinant human Langerin/CD207 protein | NKMAX ATGP3330 product information

product summary

company name :

NKMAX

product type :

protein

product name :

Recombinant human Langerin/CD207 protein

catalog :

ATGP3330

quantity :

10 ug

price :

80 USD

more info or order :

NKMAX product webpage

product information

Product Type :

Proteins

Item Name :

Recombinant human Langerin/CD207 protein

Domain :

65-328aa

Catalog number (SKU) :

ATGP3330

NCBI :

NP_056532

Description :

CD207, also known as C-type lectin domain family 4 member K, is a type 2 transmembrane glycoprotein. This protein is used as a marker for Langerhans cell which represent the immature dendritic cells in the epidermis. Also, it internalizes endogenous proteins such as type 1 procollagen. Internalization by Langerhans cell is thought to lead to suppression of self reactions. CD207 meditates endocytosis of non-peptide antigens containing mannose, N-acetyl glucosamine and fucose that are expressed by mycobacteria and fungae. Recombinant human CD207, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.

Alternative Names :

C-type lectin domain family 4 member K, Langerin, CLEC4K

Concentration :

1mg/ml (determined by absorbance at 280nm)

Formulation :

Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol

Storage :

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

General References :

Ward EM., et al. (2006) J. Biol. Chem. 281:15450-15456.;; Chabrol E., et al. (2012) PLoS ONE. 7:E50722.

Purity :

> 90% by SDS-PAGE

Applications :

SDS-PAGE

Antigen Species :

Human

Gene Category :

Signal Transduction

Molecular Weight :

30.9 kDa (273aa)

Endotoxin :

< 1 EU per 1ug of protein (determined by LAL method)

Amino Acid Sequence :

PRFMGTI SDVKTNVQLL KGRVDNISTL DSEIKKNSDG MEAAGVQIQM VNESLGYVRS QFLKLKTSVE KANAQIQILT RSWEEVSTLN AQIPELKSDL EKASALNTKI RALQGSLENM SKLLKRQNDI LQVVSQGWKY FKGNFYYFSL IPKTWYSAEQ FCVSRNSHLT SVTSESEQEF LYKTAGGLIY WIGLTKAGME GDWSWVDDTP FNKVQSARFW IPGEPNNAGN NEHCGNIKAP SLQAWNDAPC DKTFLFICKR PYVPSEP

Tag :

His-Tag

Expression System :

Baculovirus

Predicted nterm :

Ala

Product Type Name :

Recombinant Protein

UniProt No. :

Q9UJ71

Internal Search Terms :

Langerin, CD207, C-type lectin domain family 4 member K, Langerin, CLEC4K,ATGP3330-10ug,ATGP3330-20ug,ATGP3330-50ug,ATGP3330-100ug,ATGP3330-250ug,ATGP3330-500ug,ATGP3330-1mg,ATGP3330-10,ATGP3330-20,ATGP3330-50,ATGP3330-100,ATGP3330-250,ATGP3330-500,ATGP3330-1

more info or order :

NKMAX product webpage