Recombinant human 4-1BB/CD137/TNFRSF9 protein | NKMAX ATGP3303 product information

product summary

company name :

NKMAX

product type :

protein

product name :

Recombinant human 4-1BB/CD137/TNFRSF9 protein

catalog :

ATGP3303

quantity :

10 ug

price :

88 USD

more info or order :

NKMAX product webpage

product information

Product Type :

Proteins

Item Name :

Recombinant human 4-1BB/CD137/TNFRSF9 protein

Domain :

18-186aa

Catalog number (SKU) :

ATGP3303

NCBI :

NP_001552

Description :

TNFRSF9, also known as tumor necrosis factor receptor superfamily member 9, is a member of the TNF-receptor superfamily. This receptor contributes to the clonal expansion, survival, and development of T cells. It can also induce proliferation in peripheral monocytes, enhance T cell apoptosis induced by TCR/CD3 triggered activation, and regulate CD28 co-stimulation to promote Th1 cell responses. The expression of this receptor is induced by lymphocyte activation. TRAF adaptor proteins have been shown to bind to this receptor and transduce the signals leading to activation of NF-kappaB. Recombinant human TNFRSF9, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.

Alternative Names :

Tumor necrosis factor receptor superfamily member 9, 4-1BB ligand receptor, CDw137, T-cell antigen 4-1BB homolog, T-cell antigen ILA, CD137

Concentration :

0.5mg/ml (determined by absorbance at 280nm)

Formulation :

Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol

Storage :

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

General References :

Litjens NH., et al. (2013) Clin. Exp. Immunol. 174:179-191.;; Lee SJ., et al. (2013) Eur. J. Immunol. 43:1839-1848.

Purity :

> 90% by SDS-PAGE

Bioactivity Comment Only :

Measured by its binding ability in a functional ELISA with Human TNFSF9 (CAT# ATGP0308). The ED50 range ≤ 50 ng/ml.

Applications :

SDS-PAGE, Bioactivity

Antigen Species :

Human

Gene Category :

Immunology

Molecular Weight :

45.3 kDa (411aa)

Endotoxin :

< 1 EU per 1ug of protein (determined by LAL method)

Bioactivity Comment and Pics :

Human TNFSF9 (CAT# ATGP0308) is coated at 2 ug/ml (100 ul/well) can bind Human TNFRSF9. The ED50 range ≤ 50 ng/ml.

Amino Acid Sequence :

FERTRSL QDPCSNCPAG TFCDNNRNQI CSPCPPNSFS SAGGQRTCDI CRQCKGVFRT RKECSSTSNA ECDCTPGFHC LGAGCSMCEQ DCKQGQELTK KGCKDCCFGT FNDQKRGICR PWTNCSLDGK SVLVNGTKER DVVCGPSPAD LSPGASSVTP PAPAREPGHS PQ

Tag :

hIgG-His-Tag

Expression System :

Baculovirus

Predicted nterm :

Ala

Product Type Name :

Recombinant Protein

UniProt No. :

Q07011

Internal Search Terms :

41BB, TNFRSF9, TNFRSF9, Ly63, 4-1BB, ILA, CD137, CDw137,ATGP3303-10ug,ATGP3303-20ug,ATGP3303-50ug,ATGP3303-100ug,ATGP3303-250ug,ATGP3303-500ug,ATGP3303-1mg,ATGP3303-10,ATGP3303-20,ATGP3303-50,ATGP3303-100,ATGP3303-250,ATGP3303-500,ATGP3303-1

more info or order :

NKMAX product webpage