protein

Recombinant mouse FGF-21 protein

ATGP3300

10 ug

80 USD

Recombinant mouse FGF-21 protein

29-210aa

ATGP3300

NP_064397

FGF21, also known as fibroblast growth factor 21, is a member of the fibroblast growth factor family. It has a hydrophobic amino terminus, which is a typical signal sequence, and appears to be a secreted protein. It stimulates glucose uptake in differentiated adipocytes via the induction of glucose transporter SLC2A1/GLUT1 expression. Recombinant mouse FGF21, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.

Fibroblast growth factor 21

0.5mg/ml (determined by absorbance at 280nm)

Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Kharitonenkov A., et al. (2005) J Clin Invest. 115:1627-1635.;; Yamauchi H., et al. (2006) EMBO Rep. 7:649-654.

> 90% by SDS-PAGE

SDS-PAGE

Mouse

Angiogenesis

21kDa (190aa)

< 1 EU per 1ug of protein (determined by LAL method)

AYPIPDSSPL LQFGGQVRQR YLYTDDDQDT EAHLEIREDG TVVGAAHRSP ESLLELKALK PGVIQILGVK ASRFLCQQPD GALYGSPHFD PEACSFRELL LEDGYNVYQS EAHGLPLRLP QKDSPNQDAT SWGPVRFLPM PGLLHEPQDQ AGFLPPEPPD VGSSDPLSMV EPLQGRSPSY AS

His-Tag

Baculovirus

Ala29

Recombinant Protein

Q9JJN1

FGF21, Fibroblast growth factor 21,ATGP3300-10ug,ATGP3300-20ug,ATGP3300-50ug,ATGP3300-100ug,ATGP3300-250ug,ATGP3300-500ug,ATGP3300-1mg,ATGP3300-10,ATGP3300-20,ATGP3300-50,ATGP3300-100,ATGP3300-250,ATGP3300-500,ATGP3300-1

Goto T, et al. The hepatokine FGF21 is crucial for peroxisome proliferator-activated receptor-α agonist-induced amelioration of metabolic disorders in obese mice. (J Biol Chem. 2017){https://pubmed.ncbi.nlm.nih.gov/28404815/}