product summary
Loading...
company name :
NKMAX
product type :
protein
product name :
Recombinant mouse Legumain/Asparaginyl Endopeptidase protein
catalog :
ATGP3295
quantity :
10 ug
price :
80 USD
more info or order :
product information
Product Type :
Proteins
Item Name :
Recombinant mouse Legumain/Asparaginyl Endopeptidase protein
Domain :
18-435aa
Catalog number (SKU) :
ATGP3295
NCBI :
NP_035305
Description :
LGMN, also known as legumain, is a lysosomal cysteine protease found in all mouse tissues, but was particularly abundant in kidney and placenta. It plays a pivotal role in the endosomal/lysosomal degradation system because the Legumain deficiency causes the accumulation of pro cathepsins B, H and L, another group of lysosomal cysteine proteases. Over expression of Legumain in tumors is significant for invasion/metastasis. Recombinant mouse LGMN, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.
Alternative Names :
Legumain, AEP, AI746452, AU022324, Prsc1
Concentration :
0.5mg/ml (determined by absorbance at 280nm)
Formulation :
Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol
Storage :
Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
General References :
Shirahama-Noda K., et al. (2003) J. Biol. Chem. 278:33194-33199.;; Liu C., et al. (2003) Cancer Res. 63:2957-2964.
Purity :
> 90% by SDS-PAGE
Applications :
SDS-PAGE
Antigen Species :
Mouse
Gene Category :
Immunology
Molecular Weight :
48.6 kDa (426aa)
Endotoxin :
< 1 EU per 1ug of protein (determined by LAL method)
Amino Acid Sequence :
VPVGVDDPED GGKHWVVIVA GSNGWYNYRH QADACHAYQI IHRNGIPDEQ IIVMMYDDIA NSEENPTPGV VINRPNGTDV YKGVLKDYTG EDVTPENFLA VLRGDAEAVK GKGSGKVLKS GPRDHVFIYF TDHGATGILV FPNDDLHVKD LNKTIRYMYE HKMYQKMVFY IEACESGSMM NHLPDDINVY ATTAANPKES SYACYYDEER GTYLGDWYSV NWMEDSDVED LTKETLHKQY HLVKSHTNTS HVMQYGNKSI STMKVMQFQG MKHRASSPIS LPPVTHLDLT PSPDVPLTIL KRKLLRTNDV KESQNLIGQI QQFLDARHVI EKSVHKIVSL LAGFGETAER HLSERTMLTA HDCYQEAVTH FRTHCFNWHS VTYEHALRYL YVLANLCEAP YPIDRIEMAM DKVCLSHYLE HHHHHH
Tag :
His-Tag
Expression System :
Baculovirus
Predicted nterm :
Val18
Product Type Name :
Recombinant Protein
UniProt No. :
O89017
Internal Search Terms :
Legumain, Asparaginyl Endopeptidase, Legumain, AEP, AI746452, AU022324, Prsc1,ATGP3295-10ug,ATGP3295-20ug,ATGP3295-50ug,ATGP3295-100ug,ATGP3295-250ug,ATGP3295-500ug,ATGP3295-1mg,ATGP3295-10,ATGP3295-20,ATGP3295-50,ATGP3295-100,ATGP3295-250,ATGP3295-500,ATGP3295-1
more info or order :
company information
NKMAX
SNUH Health Care Innovation Park 6F
172 Dolma-ro, Bundang-gu
Seongnam-si, Gyeonggi-do
https://www.nkmaxbio.com172 Dolma-ro, Bundang-gu
Seongnam-si, Gyeonggi-do
82-31-8017-8114
headquarters: South Korea
NKMAX Co. Ltd. is a biotech company that manufactures and supplies a unique line of quality proteins and antibodies worldwide to both researchers and retailers.