Recombinant human beta -Galactosidase-1/GLB1 protein | NKMAX ATGP3290 product information

product summary

company name :

NKMAX

product type :

protein

product name :

Recombinant human beta -Galactosidase-1/GLB1 protein

catalog :

ATGP3290

quantity :

10 ug

price :

240 USD

more info or order :

NKMAX product webpage

product information

Product Type :

Proteins

Item Name :

Recombinant human beta -Galactosidase-1/GLB1 protein

Domain :

24-677aa

Catalog number (SKU) :

ATGP3290

NCBI :

NP_000395.2

Description :

GLB1, also known as beta-galactosidase, is a lysosomal B-galactosidase that hydrolyzes the terminal B-galactose form ganglioside and keratin sulfate. It plays functional roles in the formation of extracellular elastic fibers (elastogenesis) and in the development of connective tissue. It seems to be identical to the elastin-binding protein (EBP), a major component of the non-integrin cell surface receptor expressed on fibroblasts, smooth muscle cells, chondroblasts, leukocytes, and certain cancer cell types. In elastin producing cells, it associates with tropoelastin intracellularly and functions as a recycling molecular chaperone which facilitates the secretions of tropoelastin and its assembly into elastic fibers. Recombinant human GLB1, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.

Alternative Names :

GLB1, EBP, ELNR1, MPS4B

Concentration :

0.25mg/ml (determined by absorbance at 280nm)

Formulation :

Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol

Storage :

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

General References :

Hofer D., et al. (2009) Hum. Mutat 30:1214-1221.;; Kaye E.M., et al. (1997) J. Child Neurol. 12:242-247.

Purity :

> 90% by SDS-PAGE

Applications :

SDS-PAGE

Antigen Species :

Human

Gene Category :

Metabolism

Molecular Weight :

74.6 kDa (662aa)

Endotoxin :

< 1 EU per 1ug of protein (determined by LAL method)

Amino Acid Sequence :

LRNATQRMFE IDYSRDSFLK DGQPFRYISG SIHYSRVPRF YWKDRLLKMK MAGLNAIQTY VPWNFHEPWP GQYQFSEDHD VEYFLRLAHE LGLLVILRPG PYICAEWEMG GLPAWLLEKE SILLRSSDPD YLAAVDKWLG VLLPKMKPLL YQNGGPVITV QVENEYGSYF ACDFDYLRFL QKRFRHHLGD DVVLFTTDGA HKTFLKCGAL QGLYTTVDFG TGSNITDAFL SQRKCEPKGP LINSEFYTGW LDHWGQPHST IKTEAVASSL YDILARGASV NLYMFIGGTN FAYWNGANSP YAAQPTSYDY DAPLSEAGDL TEKYFALRNI IQKFEKVPEG PIPPSTPKFA YGKVTLEKLK TVGAALDILC PSGPIKSLYP LTFIQVKQHY GFVLYRTTLP QDCSNPAPLS SPLNGVHDRA YVAVDGIPQG VLERNNVITL NITGKAGATL DLLVENMGRV NYGAYINDFK GLVSNLTLSS NILTDWTIFP LDTEDAVRSH LGGWGHRDSG HHDEAWAHNS SNYTLPAFYM GNFSIPSGIP DLPQDTFIQF PGWTKGQVWI NGFNLGRYWP ARGPQLTLFV PQHILMTSAP NTITVLELEW APCSSDDPEL CAVTFVDRPV IGSSVTYDHP SKPVEKRLMP PPPQKNKDSW LDHV

Tag :

His-Tag

Expression System :

Baculovirus

Product Type Name :

Recombinant Protein

UniProt No. :

P16278

Internal Search Terms :

b-Galactosidase1, GLB1,ATGP3290-10ug,ATGP3290-20ug,ATGP3290-50ug,ATGP3290-100ug,ATGP3290-250ug,ATGP3290-500ug,ATGP3290-1mg,ATGP3290-10,ATGP3290-20,ATGP3290-50,ATGP3290-100,ATGP3290-250,ATGP3290-500,ATGP3290-1

more info or order :

NKMAX product webpage