product summary
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company name :
NKMAX
product type :
protein
product name :
Recombinant human Cystatin E/M protein
catalog :
ATGP3263
quantity :
10 ug
price :
57 USD
more info or order :
product information
Product Type :
Proteins
Item Name :
Recombinant human Cystatin E/M protein
Domain :
29-149aa
Catalog number (SKU) :
ATGP3263
NCBI :
NP_001314.1
Description :
CST6 is a member of the type 2 cystatin family. Some of the members are active cysteine protease inhibitors, while cystatin E/M moderate the inhibition of cathepsin B but is not active against cathepsin C. CST6 is secretable proteins that influence osteogenesis and bone resorption, regulation of the insulin and hepatocyte growth factor receptors, and the response to systemic inflammation. Recombinant human CST6 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.
Alternative Names :
Cystatin-M, Cystatin E/M
Concentration :
0.5mg/ml (determined by Bradford assay)
Formulation :
Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 10% glycerol, 1mM DTT, 0.1M NaCl.
Storage :
Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
General References :
Ni J., et al. (1997) J Biol Chem. 272(16):10853-8.;; Saitoh E., et al. (1988) Biol Chem Hoppe Seyler. 369:191-7.
Purity :
> 90% by SDS-PAGE
Bioactivity Comment Only :
The IC50 value is < 20nM. The inhibitory function of Cystatin 6 on protease activity of papain was measured by a fluorometric assay using Z-FR-AMC at pH 7.5 at 25C.
Applications :
SDS-PAGE, Enzyme Activity
Antigen Species :
Human
Gene Category :
Cardiovascular
Molecular Weight :
15.9 kDa (142aa) confirmed by MALDI-TOF
Bioactivity Comment and Pics :
The IC50 value is < 20nM. The inhibitory function of Cystatin 6 on protease activity of papain was measured by a fluorometric assay using Z-FR-AMC at pH 7.5 at 25C.
Amino Acid Sequence :
RPQERMVGE LRDLSPDDPQ VQKAAQAAVA SYNMGSNSIY YFRDTHIIKA QSQLVAGIKY FLTMEMGSTD CRKTRVTGDH VDLTTCPLAA GAQQEKLRCD FEVLVVPWQN SSQLLKHNCV QM
Tag :
His-Tag
Expression System :
E.coli
Product Type Name :
Recombinant Protein
UniProt No. :
Q15828
Internal Search Terms :
Cystatin E, M, Cystatin-M, Cystatin E/M, ATGP1146,ATGP3263-10ug,ATGP3263-20ug,ATGP3263-50ug,ATGP3263-100ug,ATGP3263-250ug,ATGP3263-500ug,ATGP3263-1mg,ATGP3263-10,ATGP3263-20,ATGP3263-50,ATGP3263-100,ATGP3263-250,ATGP3263-500,ATGP3263-1
more info or order :
company information
NKMAX
SNUH Health Care Innovation Park 6F
172 Dolma-ro, Bundang-gu
Seongnam-si, Gyeonggi-do
https://www.nkmaxbio.com172 Dolma-ro, Bundang-gu
Seongnam-si, Gyeonggi-do
82-31-8017-8114
headquarters: South Korea
NKMAX Co. Ltd. is a biotech company that manufactures and supplies a unique line of quality proteins and antibodies worldwide to both researchers and retailers.