Recombinant human CRACC/SLAMF7 protein | NKMAX ATGP3258 product information

product summary

company name :

NKMAX

product type :

protein

product name :

Recombinant human CRACC/SLAMF7 protein

catalog :

ATGP3258

quantity :

10 ug

price :

80 USD

more info or order :

NKMAX product webpage

product information

Product Type :

Proteins

Item Name :

Recombinant human CRACC/SLAMF7 protein

Domain :

23-226aa

Catalog number (SKU) :

ATGP3258

NCBI :

NP_067004

Description :

SLAMF7, also known as SLAM family member 7, is a single-pass type 1 membrane protein and a member of the CS2 family of cell surface receptors. Isoform 1 of this protein mediates NK cell activation through a SH2D1A-independent extracellular signal-regulated ERK-mediated pathway. It may play a role in lymphocyte adhesion. SLAMF7 can exert activating of inhibitory influences on cells of the immune system depending on cellular context and the availability of effector proteins. Recombinant human SLAMF7, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.

Alternative Names :

SLAMF7, CD2 subset 1, CD2-like receptor-activating cytotoxic cells, CRACC, CS1, CD319, Membrane protein FOAP-12, Novel Ly9, Protein 19A

Concentration :

0.5mg/ml (determined by absorbance at 280nm)

Formulation :

Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol

Storage :

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

General References :

Kim JR et al., (2013) Inflamm. Res. 62(8):765-772.;; Kramer B et al., (2013) Infect. Immun. 81(3):690-696.

Purity :

> 95% by SDS-PAGE

Applications :

SDS-PAGE

Antigen Species :

Human

Gene Category :

Immunology

Molecular Weight :

23.4 kDa (212aa)

Endotoxin :

< 1 EU per 1ug of protein (determined by LAL method)

Amino Acid Sequence :

SGPVKELVGS VGGAVTFPLK SKVKQVDSIV WTFNTTPLVT IQPEGGTIIV TQNRNRERVD FPDGGYSLKL SKLKKNDSGI YYVGIYSSSL QQPSTQEYVL HVYEHLSKPK VTMGLQSNKN GTCVTNLTCC MEHGEEDVIY TWKALGQAAN ESHNGSILPI SWRWGESDMT FICVARNPVS RNFSSPILAR KLCEGAADDP DSSM

Tag :

His-Tag

Expression System :

Baculovirus

Product Type Name :

Recombinant Protein

UniProt No. :

Q9NQ25

Internal Search Terms :

CRACSLAMF7, SLAMF7, CD2 subset 1, CD2-like receptor-activating cytotoxic cells, CRACC, CS1, CD319,ATGP3258-10ug,ATGP3258-20ug,ATGP3258-50ug,ATGP3258-100ug,ATGP3258-250ug,ATGP3258-500ug,ATGP3258-1mg,ATGP3258-10,ATGP3258-20,ATGP3258-50,ATGP3258-100,ATGP3258-250,ATGP3258-500,ATGP3258-1

References with this Product :

Kikuchi J, et al. Soluble SLAMF7 promotes the growth of myeloma cells via homophilic interaction with surface SLAMF7. (Leukemia. 2020){https://pubmed.ncbi.nlm.nih.gov/31358854/}

more info or order :

NKMAX product webpage