Recombinant mouse Galectin-2/LGALS2 protein | NKMAX ATGP3247 product information

product summary

company name :

NKMAX

product type :

protein

product name :

Recombinant mouse Galectin-2/LGALS2 protein

catalog :

ATGP3247

quantity :

4 ug

price :

30 USD

more info or order :

NKMAX product webpage

product information

Product Type :

Proteins

Item Name :

Recombinant mouse Galectin-2/LGALS2 protein

Domain :

1-130aa

Catalog number (SKU) :

ATGP3247

NCBI :

NP_079898

Description :

Galectin 2, also known as Lgals2, belongs to the galectins family. Galectins are a family of soluble beta-galactoside-binding animal lectins that modulate cell-to-cell adhesion and cell-to-extracellular matrix (ECM) interactions and play a role in tumor progression, pre-mRNA splicing and apoptosis. Lgals2 is a monomeric or homodimeric prototype galectin that is expressed in hepatoma, stomach epithelial cells and in colorectal and neural tumors. It induces apoptosis in activated T cells and binds to the cytokine lymphotoxin-a (LTA) with possible implications in risk of myocardial infarction. Human and mouse Lgals2 share approximately 65% amino acid sequence similarity. Recombinant Mouse Lgals2 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

Alternative Names :

Galectin 2, 2200008F12Rik, AI324147, Gal-2

Concentration :

1mg/ml (determined by Bradford assay)

Formulation :

Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 0.1M NaCl, 10% glycerol,1mM DTT

Storage :

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

General References :

Mehrabian M., et al. (1993) Genomics. 15:412-420.;; Cornillot J D., et al. (1998) Glycobiology. 8:425-432.

Purity :

> 95% by SDS-PAGE

Bioactivity Comment Only :

The ED50 for this effect is equal or higher than 20ug/ml. Measured by its ability to agglutinate human red blood cells.

Applications :

SDS-PAGE, Bioactivity

Antigen Species :

Mouse

Gene Category :

Signal Transduction

Molecular Weight :

17.3 kDa (153aa) confirmed by MALDI-TOF

Bioactivity Comment and Pics :

The ED50 for this effect is equal or higher than 20 ug/ml. Measured by its ability to agglutinate human red blood cells.

Amino Acid Sequence :

MGSSHHHHHH SSGLVPRGSH MGSMSEKFEV KDLNMKPGMS LKIKGKIHND VDRFLINLGQ GKETLNLHFN PRFDESTIVC NTSEGGRWGQ EQRENHMCFS PGSEVKITIT FQDKDFKVTL PDGHQLTFPN RLGHNQLHYL SMGGLQISSF KLE

Tag :

His-Tag

Expression System :

E.coli

Product Type Name :

Recombinant Protein

UniProt No. :

Q9CQW5

Internal Search Terms :

Galectin2, Galectin 2, 2200008F12Rik, AI324147,ATGP3247-10ug,ATGP3247-20ug,ATGP3247-50ug,ATGP3247-100ug,ATGP3247-250ug,ATGP3247-500ug,ATGP3247-1mg,ATGP3247-10,ATGP3247-20,ATGP3247-50,ATGP3247-100,ATGP3247-250,ATGP3247-500,ATGP3247-1

more info or order :

NKMAX product webpage