Recombinant human alpha-Galactosidase A/GLA protein | NKMAX ATGP3225 product information

product summary

company name :

NKMAX

product type :

protein

product name :

Recombinant human alpha-Galactosidase A/GLA protein

catalog :

ATGP3225

quantity :

10 ug

price :

105 USD

more info or order :

NKMAX product webpage

product information

Product Type :

Proteins

Item Name :

Recombinant human alpha-Galactosidase A/GLA protein

Domain :

32-429aa

Catalog number (SKU) :

ATGP3225

NCBI :

NP_000160

Description :

GLA, also known as alpha-galactosidase A, is homodimeric glycoprotein that hydrolyses the terminal alpha-galactosyl moieties from glycolipids and glycoproteins. It can catalyze the hydrolysis of melibiose into galactose and glucose. A variety of mutations in this gene affect the synthesis, processing, and stability of this enzyme, which causes Fabry disease, a rare lysosomal storage disorder that results from a failure to catabolize alpha-D-galactosyl glycolipid moieties. Recombinant human GLA, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.

Alternative Names :

GLA, GALA

Concentration :

0.5mg/ml (determined by absorbance at 280nm)

Formulation :

Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol

Storage :

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

General References :

Garman S.C., et al. (2004) J. Mol. Biol. 337:319-335.;; Sakuraba H., et al. (1990) Am. J. Hum. Genet. 47:784-789.

Purity :

> 90% by SDS-PAGE

Applications :

SDS-PAGE

Antigen Species :

Human

Gene Category :

Cardiovascular

Molecular Weight :

46.4 kDa (406aa)

Endotoxin :

< 1 EU per 1ug of protein (determined by LAL method)

Amino Acid Sequence :

LDNGLARTPT MGWLHWERFM CNLDCQEEPD SCISEKLFME MAELMVSEGW KDAGYEYLCI DDCWMAPQRD SEGRLQADPQ RFPHGIRQLA NYVHSKGLKL GIYADVGNKT CAGFPGSFGY YDIDAQTFAD WGVDLLKFDG CYCDSLENLA DGYKHMSLAL NRTGRSIVYS CEWPLYMWPF QKPNYTEIRQ YCNHWRNFAD IDDSWKSIKS ILDWTSFNQE RIVDVAGPGG WNDPDMLVIG NFGLSWNQQV TQMALWAIMA APLFMSNDLR HISPQAKALL QDKDVIAINQ DPLGKQGYQL RQGDNFEVWE RPLSGLAWAV AMINRQEIGG PRSYTIAVAS LGKGVACNPA CFITQLLPVK RKLGFYEWTS RLRSHINPTG TVLLQLENTM QMSLKDLLVE HHHHHH

Tag :

His-Tag

Expression System :

Baculovirus

Product Type Name :

Recombinant Protein

UniProt No. :

P06280

Internal Search Terms :

a-Galactosidase A, GLA, GLA, GALA,ATGP3225-10ug,ATGP3225-20ug,ATGP3225-50ug,ATGP3225-100ug,ATGP3225-250ug,ATGP3225-500ug,ATGP3225-1mg,ATGP3225-10,ATGP3225-20,ATGP3225-50,ATGP3225-100,ATGP3225-250,ATGP3225-500,ATGP3225-1

more info or order :

NKMAX product webpage