Recombinant human CD31/PECAM1 protein | NKMAX ATGP3214 product information

product summary

company name :

NKMAX

product type :

protein

product name :

Recombinant human CD31/PECAM1 protein

catalog :

ATGP3214

quantity :

10 ug

price :

83 USD

more info or order :

NKMAX product webpage

product information

Product Type :

Proteins

Item Name :

Recombinant human CD31/PECAM1 protein

Domain :

28-601aa

Catalog number (SKU) :

ATGP3214

NCBI :

NP_000433

Description :

PECAM1, also known as platelet endothelial cell adhesion molecule, induces susceptibility to atherosclerosis. It prevents phagocyte ingestion of closely apposed viable cells by transmitting detachment signals, and changes function on apoptosis, promoting tethering of dying cells to phagocytes. The encounter of a viable cell with a phagocyte via the homophilic interaction of PECAM1 on both cell surfaces leads to the viable cell's active repulsion from the phagocyte. Recombinant human PECAM1, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.

Alternative Names :

CD31/EndoCAM, CD31, EndoCAM, GPIIA', PECA1, PECAM1, PECAM-1, Platelet endothelial cell adhesion molecule 1

Concentration :

0.25mg/ml (determined by absorbance at 280nm)

Formulation :

Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol

Storage :

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

General References :

Brown S., et al. (2002) Nature. 418:200-203.;; Dasgupta B., et al. (2009) J Immunol. 182:5041-5051.

Purity :

> 95% by SDS-PAGE

Bioactivity Comment Only :

Measured by the ability of the immobilized protein to support the adhesion of Jurkat human acute T cell leukemia cells. When cells are added to human CD31 coated plates 5 ug/ml. This effect is more to 40%.

Applications :

SDS-PAGE, Bioactivity

Antigen Species :

Human

Gene Category :

Cardiovascular

Molecular Weight :

65.5 kDa (582aa)

Endotoxin :

< 1 EU per 1ug of protein (determined by LAL method)

Bioactivity Comment and Pics :

Human CD31 stimulates cell adhesion of the Jurkat human acute T cell leukemia cells. This effect is more to 40%.

Amino Acid Sequence :

QENSFTINSV DMKSLPDWTV QNGKNLTLQC FADVSTTSHV KPQHQMLFYK DDVLFYNISS MKSTESYFIP EVRIYDSGTY KCTVIVNNKE KTTAEYQVLV EGVPSPRVTL DKKEAIQGGI VRVNCSVPEE KAPIHFTIEK LELNEKMVKL KREKNSRDQN FVILEFPVEE QDRVLSFRCQ ARIISGIHMQ TSESTKSELV TVTESFSTPK FHISPTGMIM EGAQLHIKCT IQVTHLAQEF PEIIIQKDKA IVAHNRHGNK AVYSVMAMVE HSGNYTCKVE SSRISKVSSI VVNITELFSK PELESSFTHL DQGERLNLSC SIPGAPPANF TIQKEDTIVS QTQDFTKIAS KSDSGTYICT AGIDKVVKKS NTVQIVVCEM LSQPRISYDA QFEVIKGQTI EVRCESISGT LPISYQLLKT SKVLENSTKN SNDPAVFKDN PTEDVEYQCV ADNCHSHAKM LSEVLRVKVI APVDEVQISI LSSKVVESGE DIVLQCAVNE GSGPITYKFY REKEGKPFYQ MTSNATQAFW TKQKASKEQE GEYYCTAFNR ANHASSVPRS KILTVRVILA PWKK

Tag :

His-Tag

Expression System :

Baculovirus

Product Type Name :

Recombinant Protein

UniProt No. :

P16284

Internal Search Terms :

CD31, PECAM1, PECAM1, CD31, CD31/EndoCAM, endoCAM, GPIIA', PECA1, PECAM-1,ATGP3214-10ug,ATGP3214-20ug,ATGP3214-50ug,ATGP3214-100ug,ATGP3214-250ug,ATGP3214-500ug,ATGP3214-1mg,ATGP3214-10,ATGP3214-20,ATGP3214-50,ATGP3214-100,ATGP3214-250,ATGP3214-500,ATGP3214-1

more info or order :

NKMAX product webpage