Recombinant mouse Ephrin-B2 protein | NKMAX ATGP3212 product information

product summary

company name :

NKMAX

product type :

protein

product name :

Recombinant mouse Ephrin-B2 protein

catalog :

ATGP3212

quantity :

4 ug

price :

80 USD

more info or order :

NKMAX product webpage

product information

Product Type :

Proteins

Item Name :

Recombinant mouse Ephrin-B2 protein

Domain :

29-232aa

Catalog number (SKU) :

ATGP3212

NCBI :

NP_034241

Description :

EFNB2, also known as ephrin-B2, is cell surface transmembrane ligand for Eph receptors, a family of receptor tyrosine kinases which are crucial for migration, repulsion and adhesion during neuronal, vascular and epithelial development. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. It binds to receptor tyrosine kinase including EPHA4, EPHA3 and EPHB4. Together with EPHB4 plays a central role in heart morphogenesis and angiogenesis through regulation of cell adhesion and cell migration. EPHB4-mediated forward signaling controls cellular repulsion and segregation from EFNB2-expressing cells. It may play a role in constraining the orientation of longitudinally projecting axons. Recombinant mouse EFNB2, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.

Alternative Names :

Efnb2, ELF-2, Epl5, Eplg5, Htk-L, LERK-5, Lerk5, NLERK-1, EPH-related receptor tyrosine kinase ligand 5, HTK ligand

Concentration :

0.5mg/ml (determined by absorbance at 280nm)

Formulation :

Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol

Storage :

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

General References :

Bergemann A. D., et al. (1995) Mol. Cell. Biol. 15: 4921-4929.;; Imondi R., et al. (2000) Development 127:1397-1410.

Purity :

> 90% by SDS-PAGE

Applications :

SDS-PAGE

Antigen Species :

Mouse

Gene Category :

Cardiovascular

Molecular Weight :

23.4 kDa (212aa)

Endotoxin :

< 1 EU per 1ug of protein (determined by LAL method)

Amino Acid Sequence :

RSIVLEPIYW NSSNSKFLPG QGLVLYPQIG DKLDIICPKV DSKTVGQYEY YKVYMVDKDQ ADRCTIKKEN TPLLNCARPD QDVKFTIKFQ EFSPNLWGLE FQKNKDYYII STSNGSLEGL DNQEGGVCQT RAMKILMKVG QDASSAGSAR NHGPTRRPEL EAGTNGRSST TSPFVKPNPG SSTDGNSAGH SGNNLLGSEV ALFALEHHHH HH

Tag :

His-Tag

Expression System :

Baculovirus

Product Type Name :

Recombinant Protein

UniProt No. :

P52800

Internal Search Terms :

Ephrin-B2, Efnb2, ELF-2, Epl5, Eplg5, Htk-L, LERK-5, Lerk5, NLERK-1,ATGP3212-10ug,ATGP3212-20ug,ATGP3212-50ug,ATGP3212-100ug,ATGP3212-250ug,ATGP3212-500ug,ATGP3212-1mg,ATGP3212-10,ATGP3212-20,ATGP3212-50,ATGP3212-100,ATGP3212-250,ATGP3212-500,ATGP3212-1

more info or order :

NKMAX product webpage