Recombinant human Erythropoietin/EPO protein | NKMAX ATGP3208 product information

product summary

company name :

NKMAX

product type :

protein

product name :

Recombinant human Erythropoietin/EPO protein

catalog :

ATGP3208

quantity :

10 ug

price :

64 USD

more info or order :

NKMAX product webpage

product information

Product Type :

Proteins

Item Name :

Recombinant human Erythropoietin/EPO protein

Domain :

28-193aa

Catalog number (SKU) :

ATGP3208

NCBI :

NP_000790.1

Description :

EPO, also known as erythropoietin, is a glycoprotein hormone in the type I cytokine family and is related to thrombopoietin. Its three N-glycosylation sites, four alpha helices, and N- to C-terminal disulfide bond are conserved across species. It is primarily produced in the kidney by a population of fibroblast-like cortical interstitial cells adjacent to the proximal tubules. This protein can be found in the plasma and regulates red cell production by promoting erythroid differentiation and initiating hemoglobin synthesis. It also has neuroprotective activity against a variety of potential brain injuries and anti-apoptotic functions in several tissue types. Recombinant human EPO, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.

Alternative Names :

EPO, EP, MVCD2

Concentration :

0.5mg/ml (determined by absorbance at 280nm)

Formulation :

Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol

Storage :

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

General References :

Koury, M.J., et al. (2005) Exp. Hematol. 33:1263.;; Jelkmann W., et al. (2007) Eur J Haematol. 78:183-205

Purity :

> 95% by SDS-PAGE

Bioactivity Comment Only :

Measured in a cell proliferation assay using TF-1 human erythroleukemic cells. The ED50 range ≤0.5ng/ml.

Applications :

SDS-PAGE, Bioactivity

Antigen Species :

Human

Gene Category :

Angiogenesis

Molecular Weight :

19.5 kDa (174aa)

Endotoxin :

< 1 EU per 1ug of protein (determined by LAL method)

Bioactivity Comment and Pics :

Measured in a cell proliferation assay using TF-1 human erythroleukemic cells. The ED50 range ≤0.5 ng/ml.

Amino Acid Sequence :

APPRLICDSR VLERYLLEAK EAENITTGCA EHCSLNENIT VPDTKVNFYA WKRMEVGQQA VEVWQGLALL SEAVLRGQAL LVNSSQPWEP LQLHVDKAVS GLRSLTTLLR ALRAQKEAIS PPDAASAAPL RTITADTFRK LFRVYSNFLR GKLKLYTGEA CRTGDR

Tag :

His-Tag

Expression System :

Baculovirus

Product Type Name :

Recombinant Protein

UniProt No. :

P01588

Internal Search Terms :

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more info or order :

NKMAX product webpage