product summary
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company name :
NKMAX
product type :
protein
product name :
Recombinant human Growth Hormone R/GHR protein
catalog :
ATGP3207
quantity :
10 ug
price :
80 USD
more info or order :
product information
Product Type :
Proteins
Item Name :
Recombinant human Growth Hormone R/GHR protein
Domain :
19-264aa
Catalog number (SKU) :
ATGP3207
NCBI :
NP_000154
Description :
GHR, also known as growth hormone receptor, is a member of the cytokine receptor family. It binds two receptor molecules and thereby induces signal transduction through receptor dimerization. At high concentrations, growth hormone acts as an antagonist because of a large difference in affinities at the respective binding sites. This antagonist action can be enhanced further by reducing binding in the low affinity binding site. Recombinant human GHR, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.
Alternative Names :
GHR, GHBP, GHIP
Concentration :
1mg/ml (determined by absorbance at 280nm)
Formulation :
Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol
Storage :
Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
General References :
Yang N., et al. (2007) Mol Endocrinol. 21:1642-1655.;; Ross RJ., et al. (1997) Mol Endocrinol. 11:265-273.
Purity :
> 95% by SDS-PAGE
Bioactivity Comment Only :
Measured by ability to inhibit GH-induced proliferation assay using Nb2-11 Rat lymphoma cells in the presence of 1.25ng/ml of human growth hormone. The ED50 range ≤ 10ng/ml.
Applications :
SDS-PAGE, Bioactivity
Antigen Species :
Human
Gene Category :
Signal Transduction
Molecular Weight :
29.4 kDa (254aa)
Endotoxin :
< 1 EU per 1ug of protein (determined by LAL method)
Bioactivity Comment and Pics :
Human Growth Hormone R/GHR in inhibit the cell growth using Nb2-11 Rat lymphoma cells in the presence of 1.25ng/ml of human growth hormone. The ED50 range ≤ 10ng/ml.
Amino Acid Sequence :
FSGSEATAAI LSRAPWSLQS VNPGLKTNSS KEPKFTKCRS PERETFSCHW TDEVHHGTKN LGPIQLFYTR RNTQEWTQEW KECPDYVSAG ENSCYFNSSF TSIWIPYCIK LTSNGGTVDE KCFSVDEIVQ PDPPIALNWT LLNVSLTGIH ADIQVRWEAP RNADIQKGWM VLEYELQYKE VNETKWKMMD PILTTSVPVY SLKVDKEYEV RVRSKQRNSG NYGEFSEVLY VTLPQMSQFT CEEDFY
Tag :
His-Tag
Expression System :
Baculovirus
Product Type Name :
Recombinant Protein
UniProt No. :
P10912
Internal Search Terms :
Growth Hormone GHR, GHR, GHBP, GHIP,ATGP3207-10ug,ATGP3207-20ug,ATGP3207-50ug,ATGP3207-100ug,ATGP3207-250ug,ATGP3207-500ug,ATGP3207-1mg,ATGP3207-10,ATGP3207-20,ATGP3207-50,ATGP3207-100,ATGP3207-250,ATGP3207-500,ATGP3207-1
more info or order :
company information
NKMAX
SNUH Health Care Innovation Park 6F
172 Dolma-ro, Bundang-gu
Seongnam-si, Gyeonggi-do
https://www.nkmaxbio.com172 Dolma-ro, Bundang-gu
Seongnam-si, Gyeonggi-do
82-31-8017-8114
headquarters: South Korea
NKMAX Co. Ltd. is a biotech company that manufactures and supplies a unique line of quality proteins and antibodies worldwide to both researchers and retailers.