product summary
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company name :
NKMAX
product type :
protein
product name :
Recombinant mouse GP130/IL6ST protein
catalog :
ATGP3201
quantity :
10 ug
price :
80 USD
more info or order :
product information
Product Type :
Proteins
Item Name :
Recombinant mouse GP130/IL6ST protein
Domain :
23-617aa
Catalog number (SKU) :
ATGP3201
NCBI :
NP_034690
Description :
IL6st, also known as interleukin-6 receptor subunit beta, is a transmembrane protein which is the founding member of the class of all cytokine receptors. It forms one subunit of the type I cytokine receptor within the IL-6 receptor family. It is often referred to as the common gp130 subunit, and is important for signal transduction following cytokine engagement. As with other type I cytokine receptors, gp130 possesses a WSXWS amino acid motif that ensures correct protein folding and ligand binding. It interacts with Janus kinases to elicit an intracellular signal following receptor interaction with its ligand. Structurally, gp130 is composed of five fibronectin type-III domains and one immunoglobulin-like C2-type (immunoglobulin-like) domain in its extracellular portion. Recombinant mouse IL6st, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.
Alternative Names :
Interleukin-6 receptor subunit beta, IL-6R subunit beta, IL-6R-beta, IL-6RB, Interleukin-6 signal transducer, Membrane glycoprotein 130, gp130, Oncostatin-M receptor subunit alpha, CD130
Concentration :
1mg/ml (determined by absorbance at 280nm)
Formulation :
Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol
Storage :
Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
General References :
Saito M., et al. (1992) J Immunol. 148: 4066-4071.;; Murakami M., et al. (1993) Science. 260:1808-1810.
Purity :
> 95% by SDS-PAGE
Applications :
SDS-PAGE
Antigen Species :
Mouse
Gene Category :
Apoptosis
Molecular Weight :
67.7 kDa (603aa)
Endotoxin :
< 1 EU per 1ug of protein (determined by LAL method)
Amino Acid Sequence :
QLLEPCGYIY PEFPVVQRGS NFTAICVLKE ACLQHYYVNA SYIVWKTNHA AVPREQVTVI NRTTSSVTFT DVVLPSVQLT CNILSFGQIE QNVYGVTMLS GFPPDKPTNL TCIVNEGKNM LCQWDPGRET YLETNYTLKS EWATEKFPDC QSKHGTSCMV SYMPTYYVNI EVWVEAENAL GKVSSESINF DPVDKVKPTP PYNLSVTNSE ELSSILKLSW VSSGLGGLLD LKSDIQYRTK DASTWIQVPL EDTMSPRTSF TVQDLKPFTE YVFRIRSIKD SGKGYWSDWS EEASGTTYED RPSRPPSFWY KTNPSHGQEY RSVRLIWKAL PLSEANGKIL DYEVILTQSK SVSQTYTVTG TELTVNLTND RYVASLAARN KVGKSAAAVL TIPSPHVTAA YSVVNLKAFP KDNLLWVEWT PPPKPVSKYI LEWCVLSENA PCVEDWQQED ATVNRTHLRG RLLESKCYQI TVTPVFATGP GGSESLKAYL KQAAPARGPT VRTKKVGKNE AVLAWDQIPV DDQNGFIRNY SISYRTSVGK EMVVHVDSSH TEYTLSSLSS DTLYMVRMAA YTDEGGKDGP EFTFTTPKFA QGEIELEHHH HHH
Tag :
His-Tag
Expression System :
Baculovirus
Product Type Name :
Recombinant Protein
UniProt No. :
Q00560
Internal Search Terms :
Oncostatin-M receptor subunit alpha, Oncostatin M receptor subunit alpha, Membrane glycoprotein 130, Interleukin-6 signal transducer, Interleukin-6 receptor subunit beta, Interleukin 6 signal transducer, Interleukin 6 receptor subunit beta, Il6st, IL-6R-beta, IL-6RB, IL-6R subunit beta, IL6R subunit beta, IL-6R beta, IL-6R B, IL6R b, IL 6RB, IL 6R subunit beta, IL 6R beta, IL 6R B, GP130, GP 130, D13Ertd699e, CD130, CD 130, BB405851, AA389424, 5133400A03Rik, ATGP3201-10ug, ATGP3201-20ug, ATGP3201-50ug, ATGP3201-100ug, ATGP3201-250ug, ATGP3201-500ug, ATGP3201-1mg, ATGP3201-010, ATGP3201-020, ATGP3201-050, ATGP3201-100, ATGP3201-250, ATGP3201-500, ATGP3201-01M
more info or order :
company information
NKMAX
SNUH Health Care Innovation Park 6F
172 Dolma-ro, Bundang-gu
Seongnam-si, Gyeonggi-do
https://www.nkmaxbio.com172 Dolma-ro, Bundang-gu
Seongnam-si, Gyeonggi-do
82-31-8017-8114
headquarters: South Korea
NKMAX Co. Ltd. is a biotech company that manufactures and supplies a unique line of quality proteins and antibodies worldwide to both researchers and retailers.