product summary
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company name :
NKMAX
product type :
protein
product name :
Recombinant human Legumain/Asparaginyl Endopeptidase protein
catalog :
ATGP3185
quantity :
10 ug
price :
80 USD
more info or order :
product information
Product Type :
Proteins
Item Name :
Recombinant human Legumain/Asparaginyl Endopeptidase protein
Domain :
18-433aa
Catalog number (SKU) :
ATGP3185
NCBI :
NP_005597
Description :
LGMN, also known as legumain, is a cysteine endopeptidase that shows strict specificity for hydrolysis of asparaginyl bonds. It can also cleave aspartyl bonds slowly, especially under acidic conditions. It required for normal lysosomal protein degradation in renal proximal tubules. They are required for normal degradation of internalized EGFR and play a role in the regulation of cell proliferation via its role in EGFR degradation. Recombinant human LGMN, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.
Alternative Names :
LGMN, AEP, LGMN1, PRSC1
Concentration :
1mg/ml (determined by absorbance at 280nm)
Formulation :
Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol
Storage :
Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
General References :
Dall E., et al. (2012) Proc Natl Acad Sci U S A. 110:10940-10945.;; Chen JM., et al. (1996) J Biol Chem. 272:8090-8098.
Purity :
> 95% by SDS-PAGE
Applications :
SDS-PAGE
Antigen Species :
Human
Gene Category :
Immunology
Molecular Weight :
48.4 kDa (422aa)
Endotoxin :
< 1 EU per 1ug of protein (determined by LAL method)
Amino Acid Sequence :
VPIDDPEDGG KHWVVIVAGS NGWYNYRHQA DACHAYQIIH RNGIPDEQIV VMMYDDIAYS EDNPTPGIVI NRPNGTDVYQ GVPKDYTGED VTPQNFLAVL RGDAEAVKGI GSGKVLKSGP QDHVFIYFTD HGSTGILVFP NEDLHVKDLN ETIHYMYKHK MYRKMVFYIE ACESGSMMNH LPDNINVYAT TAANPRESSY ACYYDEKRST YLGDWYSVNW MEDSDVEDLT KETLHKQYHL VKSHTNTSHV MQYGNKTIST MKVMQFQGMK RKASSPVPLP PVTHLDLTPS PDVPLTIMKR KLMNTNDLEE SRQLTEEIQR HLDARHLIEK SVRKIVSLLA ASEAEVEQLL SERAPLTGHS CYPEALLHFR THCFNWHSPT YEYALRHLYV LVNLCEKPYP LHRIKLSMDH VCLGHY
Tag :
His-Tag
Expression System :
Baculovirus
Product Type Name :
Recombinant Protein
UniProt No. :
Q99538
Internal Search Terms :
Legumain, Asparaginyl Endopeptidase, LGMN, AEP, LGMN1, PRSC1,ATGP3185-10ug,ATGP3185-20ug,ATGP3185-50ug,ATGP3185-100ug,ATGP3185-250ug,ATGP3185-500ug,ATGP3185-1mg,ATGP3185-10,ATGP3185-20,ATGP3185-50,ATGP3185-100,ATGP3185-250,ATGP3185-500,ATGP3185-1
more info or order :
company information
NKMAX
SNUH Health Care Innovation Park 6F
172 Dolma-ro, Bundang-gu
Seongnam-si, Gyeonggi-do
https://www.nkmaxbio.com172 Dolma-ro, Bundang-gu
Seongnam-si, Gyeonggi-do
82-31-8017-8114
headquarters: South Korea
NKMAX Co. Ltd. is a biotech company that manufactures and supplies a unique line of quality proteins and antibodies worldwide to both researchers and retailers.