product summary
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company name :
NKMAX
product type :
protein
product name :
Recombinant rat TIMP-1 protein
catalog :
ATGP3178
quantity :
10 ug
price :
80 USD
more info or order :
product information
Product Type :
Proteins
Item Name :
Recombinant rat TIMP-1 protein
Domain :
24-217aa
Catalog number (SKU) :
ATGP3178
NCBI :
NP_446271
Description :
TIMP1, also known as metalloproteinase inhibitor 1, a tissue inhibitor of metalloproteinases, is a glycoprotein that is expressed from the several tissues of organisms. The glycoprotein is a natural inhibitor of the matrix metalloproteinases (MMPs), a group of peptidases involved in degradation of the extracellular matrix. In addition to its inhibitory role against most of the known MMPs, the encoded protein is able to promote cell proliferation in a wide range of cell types, and may also have an anti-apoptotic function. MMP1 functions as a growth factor that regulates cell differentiation, migration and cell death and activates cellular signaling cascades via CD63 and ITGB1. It plays a role in integrin signaling. Recombinant rat TIMP1, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.
Alternative Names :
Timp1, Timp, TIMP-1
Concentration :
0.5mg/ml (determined by absorbance at 280nm)
Formulation :
Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol
Storage :
Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
General References :
Uchida C et al., (2014) Biochem. Cell Biol. 92(1):77-83.;; Zhang CY et al., (2013) Acta Pharmacol. Sin. 34(10):1301-1309.
Purity :
> 90% by SDS-PAGE
Applications :
SDS-PAGE
Antigen Species :
Rat
Gene Category :
Enzymes & Proteases
Molecular Weight :
22.3 kDa (200aa)
Endotoxin :
< 1 EU per 1ug of protein (determined by LAL method)
Amino Acid Sequence :
CSCAPTHPQT AFCNSDLVIR AKFMGSPEII ETTLYQRYEI KMTKMLKGFD AVGNATGFRF AYTPAMESLC GYVHKSQNRS EEFLIAGRLR NGNLHITACS FLVPWHNLSP AQQKAFVKTY SAGCGVCTVF PCSAIPCKLE SDSHCLWTDQ ILMGSEKGYQ SDHFACLPRN PDLCTWQYLG VSMTRSLPLA KAEA
Tag :
His-Tag
Expression System :
Baculovirus
Product Type Name :
Recombinant Protein
UniProt No. :
P30120
Internal Search Terms :
TIMP1, Timp1, Timp, TIMP-1,ATGP3178-10ug,ATGP3178-20ug,ATGP3178-50ug,ATGP3178-100ug,ATGP3178-250ug,ATGP3178-500ug,ATGP3178-1mg,ATGP3178-10,ATGP3178-20,ATGP3178-50,ATGP3178-100,ATGP3178-250,ATGP3178-500,ATGP3178-1
more info or order :
company information
NKMAX
SNUH Health Care Innovation Park 6F
172 Dolma-ro, Bundang-gu
Seongnam-si, Gyeonggi-do
https://www.nkmaxbio.com172 Dolma-ro, Bundang-gu
Seongnam-si, Gyeonggi-do
82-31-8017-8114
headquarters: South Korea
NKMAX Co. Ltd. is a biotech company that manufactures and supplies a unique line of quality proteins and antibodies worldwide to both researchers and retailers.