product summary
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company name :
NKMAX
product type :
protein
product name :
Recombinant mouse RKIP/PEBP1 protein
catalog :
ATGP3172
quantity :
20 ug
price :
80 USD
more info or order :
product information
Product Type :
Proteins
Item Name :
Recombinant mouse RKIP/PEBP1 protein
Domain :
1-187aa
Catalog number (SKU) :
ATGP3172
NCBI :
NP_061346
Description :
Pebp1 also known as Phosphatidylethanolamine-binding protein 1. The protein Binds with ATP, opioids and phosphatidylethanolamine. Pebp1 exerts inhibitory activity against several serine proteases including thrombin, neuropsin, and chymotrypsin, it also inhibits the kinase activity of RAF1 by inhibiting its activation and by dissociating the RAF1/MEK complex and acting as a competitive inhibitor of MEK phosphorylation. Also, targeting Pebp1 levels can delay photoreceptor degeneration, assisting in extending the time-window for treating such rapidly progressing blindness disorder. Recombinant mouse Pebp1, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.
Alternative Names :
Phosphatidylethanolamine-binding protein 1, HCNP, Pbp, Pbp1, Pbqr, Rkip, prostatic binding protein, Raf kinase inhibitory protein, hippocampal cholinergic neurostimulating peptide
Concentration :
1mg/ml (determined by absorbance at 280nm)
Formulation :
Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol
Storage :
Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
General References :
Hengst U., et al. (2001) J Biol Chem. 276(1):535-40;; Subramanian B., et al. (2014) Invest Ophthalmol Vis Sci. 55(9):5788-94
Purity :
> 95% by SDS-PAGE
Applications :
SDS-PAGE
Antigen Species :
Mouse
Gene Category :
Cell Cycle
Molecular Weight :
23.2 kDa (210aa) confirmed by MALDI-TOF
Amino Acid Sequence :
MGSSHHHHHH SSGLVPRGSH MGSMAADISQ WAGPLCLQEV DEPPQHALRV DYAGVTVDEL GKVLTPTQVM NRPSSISWDG LDPGKLYTLV LTDPDAPSRK DPKFREWHHF LVVNMKGNDI SSGTVLSDYV GSGPPSGTGL HRYVWLVYEQ EQPLSCDEPI LSNKSGDNRG KFKVETFRKK YNLGAPVAGT CYQAEWDDYV PKLYEQLSGK
Tag :
His-Tag
Expression System :
E.coli
Product Type Name :
Recombinant Protein
UniProt No. :
P70296
Internal Search Terms :
Rkip, Raf kinase inhibitory protein, Prostatic binding protein, Phosphatidylethanolamine-binding protein 1, Phosphatidylethanolamine binding protein 1, Pbqr, Pbp1, Pbp 1, Pbp, Hippocampal cholinergic neurostimulating peptide, HCNP, ATGP3172-10ug, ATGP3172-20ug, ATGP3172-50ug, ATGP3172-100ug, ATGP3172-250ug, ATGP3172-500ug, ATGP3172-1mg, ATGP3172-010, ATGP3172-020, ATGP3172-050, ATGP3172-100, ATGP3172-250, ATGP3172-500, ATGP3172-01M
more info or order :
company information
NKMAX
SNUH Health Care Innovation Park 6F
172 Dolma-ro, Bundang-gu
Seongnam-si, Gyeonggi-do
https://www.nkmaxbio.com172 Dolma-ro, Bundang-gu
Seongnam-si, Gyeonggi-do
82-31-8017-8114
headquarters: South Korea
NKMAX Co. Ltd. is a biotech company that manufactures and supplies a unique line of quality proteins and antibodies worldwide to both researchers and retailers.