product summary
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company name :
NKMAX
product type :
protein
product name :
Recombinant mouse SDF-1/CXCL12 protein
catalog :
ATGP3159
quantity :
10 ug
price :
130 USD
more info or order :
product information
Product Type :
Proteins
Item Name :
Recombinant mouse SDF-1/CXCL12 protein
Domain :
22-89aa
Catalog number (SKU) :
ATGP3159
NCBI :
NP_068350.1
Description :
Cxcl12 also known as stromal cell-derived factor 1 isoform alpha. This protein acts as a positive regulator of monocyte migration and a negative regulator of monocyte adhesion via the LYN kinase. It stimulates migration of monocytes and T-lymphocytes through its receptors, CXCR4 and ACKR3, and decreases monocyte adherence to surfaces coated with ICAM-1, a ligand for beta-2 integrins. This protein inhibits CXCR4-mediated infection by T-cell line-adapted HIV-1. Cxcl12 protein plays a protective role after myocardial infarction. It induces down-regulation and internalization of ACKR3 expressed in various cells. Recombinant mouse Cxcl12, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques
Alternative Names :
Stromal cell-derived factor 1 isoform alpha, Stromal cell-derived factor 1, 12-O-tetradecanoylphorbol 13-acetate repressed protein 1, TPAR1, C-X-C motif chemokine 12, Pre-B cell growth-stimulating factor, PBSF, Thymic lymphoma cell-stimulating factor, TLSF, Scyb12, Sdf1, SDF-1, Sdf1a, Sdf1b
Concentration :
0.25mg/ml (determined by absorbance at 280nm)
Formulation :
Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol
Storage :
Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
General References :
Beaulande M., et al. (1998) Nucleic Acids. 26(2):521-4;; Chen T., et al. (2015) Am J Transplant. 15(3):618-27
Purity :
> 95% by SDS-PAGE
Applications :
SDS-PAGE
Antigen Species :
Mouse
Gene Category :
Hormones & Cytokines
Molecular Weight :
10.4 kDa (91aa) confirmed by MALDI-TOF
Amino Acid Sequence :
KPVSLSY RCPCRFFESH IARANVKHLK ILNTPNCALQ IVARLKNNNR QVCIDPKLKW IQEYLEKALN K
Tag :
His-Tag
Expression System :
E.coli
Product Type Name :
Recombinant Protein
UniProt No. :
P40224
Internal Search Terms :
CXCL12, SDF1, Stromal cell-derived factor 1 isoform alpha, Pbsf, Scyb12, Sdf1, Tlsf, Tpar1,ATGP3159-10ug,ATGP3159-20ug,ATGP3159-50ug,ATGP3159-100ug,ATGP3159-250ug,ATGP3159-500ug,ATGP3159-1mg,ATGP3159-10,ATGP3159-20,ATGP3159-50,ATGP3159-100,ATGP3159-250,ATGP3159-500,ATGP3159-1
more info or order :
company information
NKMAX
SNUH Health Care Innovation Park 6F
172 Dolma-ro, Bundang-gu
Seongnam-si, Gyeonggi-do
https://www.nkmaxbio.com172 Dolma-ro, Bundang-gu
Seongnam-si, Gyeonggi-do
82-31-8017-8114
headquarters: South Korea
NKMAX Co. Ltd. is a biotech company that manufactures and supplies a unique line of quality proteins and antibodies worldwide to both researchers and retailers.