Recombinant human Kallikrein 13/KLK13 protein | NKMAX ATGP3148 product information

product summary

company name :

NKMAX

product type :

protein

product name :

Recombinant human Kallikrein 13/KLK13 protein

catalog :

ATGP3148

quantity :

4 ug

price :

80 USD

more info or order :

NKMAX product webpage

product information

Product Type :

Proteins

Item Name :

Recombinant human Kallikrein 13/KLK13 protein

Domain :

17-277aa

Catalog number (SKU) :

ATGP3148

NCBI :

NP_056411

Description :

KLK13, also known as kallikrein-13, belongs to Kallikrein subfamily. Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. KLK13 is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. Expression of this gene is regulated by steroid hormones and may be useful as a marker for breast cancer. An additional transcript variant has been identified, but its full length sequence has not been determined. Recombinant human KLK13, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.

Alternative Names :

Kallikrein related peptidase 13, Kallikrein-13 Kallikrein-like protein 4, KLK-L4

Concentration :

0.5mg/ml (determined by absorbance at 280nm)

Formulation :

Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol

Storage :

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

General References :

Yousef G.M. et al., (2000) J. Biol. Chem. 275:11891-11898.;; Diamandis EP. et al., (2000) Trends Endocrinol. Metab. 11:54-60.

Purity :

> 90% by SDS-PAGE

Bioactivity Comment Only :

Specific activity is > 8,000pmol/min/ug. One unit will hydrolyze 1.0pmole of BAEE to Na-Benzoyl-L-arginine per minute at pH8.0 at 25C.

Applications :

SDS-PAGE, Enzyme Activity

Antigen Species :

Human

Gene Category :

Signal Transduction

Molecular Weight :

29.7 kDa (267aa)

Endotoxin :

< 1 EU per 1ug of protein (determined by LAL method)

Bioactivity Comment and Pics :

Specific activity is > 8,000 pmol/min/ug. One unit will hydrolyze 1.0 pmole of BAEE to Na-Benzoyl-L-arginine per minute at pH8.0 at 25C.

Amino Acid Sequence :

GGVSQESSKV LNTNGTSGFL PGGYTCFPHS QPWQAALLVQ GRLLCGGVLV HPKWVLTAAH CLKEGLKVYL GKHALGRVEA GEQVREVVHS IPHPEYRRSP THLNHDHDIM LLELQSPVQL TGYIQTLPLS HNNRLTPGTT CRVSGWGTTT SPQVNYPKTL QCANIQLRSD EECRQVYPGK ITDNMLCAGT KEGGKDSCEG DSGGPLVCNR TLYGIVSWGD FPCGQPDRPG VYTRVSRYVL WIRETIRKYE TQQQKWLKGP QHHHHHH

Tag :

His-Tag

Expression System :

Baculovirus

Product Type Name :

Recombinant Protein

UniProt No. :

Q9UKR3

Internal Search Terms :

Kallikrein13, Kallikrein 13, Kallikrein-13, KLK-L4, KLKL4, KLK L4, ATGP3148-10ug, ATGP3148-20ug, ATGP3148-50ug, ATGP3148-100ug, ATGP3148-250ug, ATGP3148-500ug, ATGP3148-1mg, ATGP3148-010, ATGP3148-020, ATGP3148-050, ATGP3148-100, ATGP3148-250, ATGP3148-500, ATGP3148-01M

more info or order :

NKMAX product webpage