Recombinant human PDIA6 protein | NKMAX ATGP3139 product information

product summary

company name :

NKMAX

product type :

protein

product name :

Recombinant human PDIA6 protein

catalog :

ATGP3139

quantity :

4 ug

price :

30 USD

more info or order :

NKMAX product webpage

product information

Product Type :

Proteins

Item Name :

Recombinant human PDIA6 protein

Domain :

20-440aa

Catalog number (SKU) :

ATGP3139

NCBI :

NP_005733

Description :

PDIA6 is a member of the protein disulfide isomerase (PDI). PDI is an enzyme in the endoplasmic reticulum in eukaryotes or periplasmic space of prokaryotes that catalyzes the formation and breakage of disulfide bonds between cysteine residues within proteins as they fold. PDIA6 function as a chaperone that inhibits aggregation of misfolded proteins. It plays a role in platelet aggregation and activation by agonists such as convulxin, collagen and thrombin. Recombinant human PDIA6 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

Alternative Names :

Protein disulfide-isomerase A6, ERP5, P5, TXNDC7

Concentration :

1mg/ml (determined by Bradford assay)

Formulation :

Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing, 50mM NaCl, 2mM DTT and 10% glycerol

Storage :

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

General References :

Jordan P.A., et al. (2005) Blood. 105:1500-1507;; Kikuchi M., et al. (2002) J. Biochem. 132:451-455

Purity :

> 90% by SDS-PAGE

Bioactivity Comment Only :

Specific activity > 10 A650/cm/min/mg. Enzymatic activity was confirmed by measuring the aggregation of insulin in the presence of DTT.

Applications :

SDS-PAGE, Enzyme Activity

Antigen Species :

Human

Gene Category :

Heat Shock Proteins

Molecular Weight :

48.5 kDa (442aa) confirmed by MALDI-TOF

Bioactivity Comment and Pics :

Specific activity > 20 A650/cm/min/mg. Enzymatic activity was confirmed by measuring the aggregation of insulin in the presence of DTT.

Amino Acid Sequence :

LYSSSDDVI ELTPSNFNRE VIQSDSLWLV EFYAPWCGHC QRLTPEWKKA ATALKDVVKV GAVDADKHHS LGGQYGVQGF PTIKIFGSNK NRPEDYQGGR TGEAIVDAAL SALRQLVKDR LGGRSGGYSS GKQGRSDSSS KKDVIELTDD SFDKNVLDSE DVWMVEFYAP WCGHCKNLEP EWAAAASEVK EQTKGKVKLA AVDATVNQVL ASRYGIRGFP TIKIFQKGES PVDYDGGRTR SDIVSRALDL FSDNAPPPEL LEIINEDIAK RTCEEHQLCV VAVLPHILDT GAAGRNSYLE VLLKLADKYK KKMWGWLWTE AGAQSELETA LGIGGFGYPA MAAINARKMK FALLKGSFSE QGINEFLREL SFGRGSTAPV GGGAFPTIVE REPWDGRDGE LPVEDDIDLS DVELDDLGKD EL

Tag :

His-Tag

Expression System :

E.coli

Product Type Name :

Recombinant Protein

UniProt No. :

Q15084

Internal Search Terms :

PDIA6, Protein disulfide-isomerase A6, ERP5, P5, TXNDC7,ATGP3139-10ug,ATGP3139-20ug,ATGP3139-50ug,ATGP3139-100ug,ATGP3139-250ug,ATGP3139-500ug,ATGP3139-1mg,ATGP3139-10,ATGP3139-20,ATGP3139-50,ATGP3139-100,ATGP3139-250,ATGP3139-500,ATGP3139-1

more info or order :

NKMAX product webpage