product summary
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company name :
NKMAX
product type :
protein
product name :
Recombinant human Cystatin D protein
catalog :
ATGP3122
quantity :
10 ug
price :
80 USD
more info or order :
product information
Product Type :
Proteins
Item Name :
Recombinant human Cystatin D protein
Domain :
26-142aa
Catalog number (SKU) :
ATGP3122
NCBI :
NP_001891.2
Description :
CST5, also known as Cystatin-D, is a novel member of the cystatin superfamily. The cystatin superfamily encompasses proteins that contain multiple cystatin-like sequences. Some of the members are active cysteine protease inhibitors, while others have lost or perhaps never acquired this inhibitory activity. There are three inhibitory families in the superfamily, including the type 1 cystatins (stefins), type 2 cystatins and the kininogens. The type 2 cystatin proteins are a class of cysteine proteinase inhibitors found in a variety of human fluids and secretions. Two alleles of the cystatin D gene (CST5), encoding protein variants with either Cys or Arg as residue 26 in their 122-residue polypeptide chains, are present in the population. Recombinant human CST5, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.
Alternative Names :
Cystatin-D
Concentration :
0.5mg/ml (determined by absorbance at 280nm)
Formulation :
Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol
Storage :
Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
General References :
Balbin M. et al. (1994) J Biol Chem. 269:23156-23162.;; Alvarez-Fernandez M. et al. (2005) J Biol Chem. 280:18221-18228.
Purity :
> 90% by SDS-PAGE
Bioactivity Comment Only :
The IC50 value is < 2.0nM. The inhibitory function of Cystatin 5 on protease activity of papain was measured by a fluorometric assay using Z-FR-AMC at pH 7.5 at 25C.
Applications :
SDS-PAGE, Enzyme Activity
Antigen Species :
Human
Gene Category :
Protease inhibitors
Molecular Weight :
14.36 kDa (123aa)
Endotoxin :
< 1 EU per 1ug of protein (determined by LAL method)
Bioactivity Comment and Pics :
The IC50 value is < 2.0nM. The inhibitory function of Cystatin 5 on protease activity of papain was measured by a fluorometric assay using Z-FR-AMC at pH 7.5 at 25C.
Amino Acid Sequence :
QSRTLAGGIH ATDLNDKSVQ RALDFAISEY NKVINKDEYY SRPLQVMAAY QQIVGGVNYY FNVKFGRTTC TKSQPNLDNC PFNDQPKLKE EEFCSFQINE VPWEDKISIL NYKCRKV
Tag :
His-Tag
Expression System :
Baculovirus
Product Type Name :
Recombinant Protein
UniProt No. :
P28325
Internal Search Terms :
Cystatin D, Cystatin-D,ATGP3122-10ug,ATGP3122-20ug,ATGP3122-50ug,ATGP3122-100ug,ATGP3122-250ug,ATGP3122-500ug,ATGP3122-1mg,ATGP3122-10,ATGP3122-20,ATGP3122-50,ATGP3122-100,ATGP3122-250,ATGP3122-500,ATGP3122-1
more info or order :
company information
NKMAX
SNUH Health Care Innovation Park 6F
172 Dolma-ro, Bundang-gu
Seongnam-si, Gyeonggi-do
https://www.nkmaxbio.com172 Dolma-ro, Bundang-gu
Seongnam-si, Gyeonggi-do
82-31-8017-8114
headquarters: South Korea
NKMAX Co. Ltd. is a biotech company that manufactures and supplies a unique line of quality proteins and antibodies worldwide to both researchers and retailers.