Recombinant human MKK6 protein | NKMAX ATGP3117 product information

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product summary

company name :

NKMAX

product type :

protein

product name :

Recombinant human MKK6 protein

catalog :

ATGP3117

quantity :

50 ug

price :

240 USD

product information

Product Type :

Proteins

Item Name :

Recombinant human MKK6 protein

Domain :

1-334aa

Catalog number (SKU) :

ATGP3117

NCBI :

NP_002749

Description :

MAP2K6, also known as dual specificity mitogen-activated protein kinase kinase 6, is a member of the dual specificity protein kinase family, which functions as a mitogen-activated protein (MAP) kinase kinase. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals. This protein phosphorylates and activates p38 MAP kinase in response to inflammatory cytokines or environmental stress. As an essential component of p38 MAP kinase mediated signal transduction pathway, this gene is involved in many cellular processes such as stress-induced cell cycle arrest, transcription activation and apoptosis. Recombinant human MAP2K6, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.

Alternative Names :

Dual specificity mitogen-activated protein kinase kinase 6, MAPKK6, MEK6, MKK6, PRKMK6, SAPKK-3, SAPKK3

Concentration :

1mg/ml (determined by absorbance at 280nm)

Formulation :

Liquid in. Phosphate-Buffered Saline (pH 7.4) 20% glycerol

Storage :

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

General References :

Chen Z, et al (2001) J Biol Chem. 276(19):16070-5.

Purity :

> 90% by SDS-PAGE

Applications :

SDS-PAGE

Antigen Species :

Human

Gene Category :

Cell Cycle

Molecular Weight :

38.3 kDa (340aa) confirmed by MALDI-TOF

Endotoxin :

< 1 EU per 1ug of protein (determined by LAL method)

Bioassay Procedure :

MSQSKGKKRN PGLKIPKEAF EQPQTSSTPP RDLDSKACIS IGNQNFEVKA DDLEPIMELG RGAYGVVEKM RHVPSGQIMA VKRIRATVNS QEQKRLLMDL DISMRTVDCP FTVTFYGALF REGDVWICME LMDTSLDKFY KQVIDKGQTI PEDILGKIAV SIVKALEHLH SKLSVIHRDV KPSNVLINAL GQVKMCDFGI SGYLVDSVAK TIDAGCKPYM APERINPELN QKGYSVKSDI WSLGITMIEL AILRFPYDSW GTPFQQLKQV VEEPSPQLPA DKFSAEFVDF TSQCLKKNSK ERPTYPELMQ HPFFTLHESK GTDVASFVKL ILGDHHHHHH

Tag :

His-Tag

Expression System :

Baculovirus

Product Type Name :

Recombinant Protein

UniProt No. :

P52564

Internal Search Terms :

MKK6, Dual specificity mitogen-activated protein kinase kinase 6, MAPKK6, MEK6, MKK6, PRKMK6, SAPKK-3, SAPKK3

Size 2 :

50 ug

List Price 2 (USD) :

240 USD