Recombinant human IL-12R beta/IL12RB1 protein | NKMAX ATGP3082 product information

product summary

company name :

NKMAX

product type :

protein

product name :

Recombinant human IL-12R beta/IL12RB1 protein

catalog :

ATGP3082

quantity :

10 ug

price :

80 USD

more info or order :

NKMAX product webpage

product information

Product Type :

Proteins

Item Name :

Recombinant human IL-12R beta/IL12RB1 protein

Domain :

24-545aa

Catalog number (SKU) :

ATGP3082

NCBI :

NP_005526.1

Description :

IL12RB1, also known as Interleukin-12 receptor subunit beta-1, is a intercellular adhesion molecule 1. This protein binds to interleukine 12 (IL12) with a low affinity, and is thought to be a part of IL12 receptor complex. It forms a disulfide-linked oligomer, which is required for its IL12 binding activity. The coexpression of this protein and IL12RB2 was shown to lead to the formation of high-affinity IL12 binding sites and reconstitution of IL12 dependent signaling. Recombinant human IL12RB1, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.

Alternative Names :

Interleukin 12 receptor subunit beta 1, IL-12 receptor subunit beta-1, IL-12R subunit beta-1, IL-12R-beta-1, IL-12 receptor beta component, IL12R, IL12RB, CD212

Concentration :

0.25mg/ml (determined by Bradford assay)

Formulation :

Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 30% glycerol, 1mM EDTA, 0.1mM PMSF.

Storage :

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

General References :

van de Vosse E. et al. (2003) Immunogenetics. 54(12):817-29.

Purity :

> 85% by SDS-PAGE

Applications :

SDS-PAGE

Antigen Species :

Human

Gene Category :

Hormones & Cytokines

Molecular Weight :

58.4 kDa (528aa)

Endotoxin :

< 1 EU per 1ug of protein (determined by LAL method)

Amino Acid Sequence :

CRTSECCFQD PPYPDADSGS ASGPRDLRCY RISSDRYECS WQYEGPTAGV SHFLRCCLSS GRCCYFAAGS ATRLQFSDQA GVSVLYTVTL WVESWARNQT EKSPEVTLQL YNSVKYEPPL GDIKVSKLAG QLRMEWETPD NQVGAEVQFR HRTPSSPWKL GDCGPQDDDT ESCLCPLEMN VAQEFQLRRR QLGSQGSSWS KWSSPVCVPP ENPPQPQVRF SVEQLGQDGR RRLTLKEQPT QLELPEGCQG LAPGTEVTYR LQLHMLSCPC KAKATRTLHL GKMPYLSGAA YNVAVISSNQ FGPGLNQTWH IPADTHTEPV ALNISVGTNG TTMYWPARAQ SMTYCIEWQP VGQDGGLATC SLTAPQDPDP AGMATYSWSR ESGAMGQEKC YYITIFASAH PEKLTLWSTV LSTYHFGGNA SAAGTPHHVS VKNHSLDSVS VDWAPSLLST CPGVLKEYVV RCRDEDSKQV SEHPVQPTET QVTLSGLRAG VAYTVQVRAD TAWLRGVWSQ PQRFSIEVQV SD

Tag :

His-Tag

Expression System :

Baculovirus

Product Type Name :

Recombinant Protein

UniProt No. :

P42701

Internal Search Terms :

IL12 R b1, Interleukin-12 receptor subunit beta-1 isoform 1, CD212, IL-12R-BETA1, IL12RB,ATGP3082-10ug,ATGP3082-20ug,ATGP3082-50ug,ATGP3082-100ug,ATGP3082-250ug,ATGP3082-500ug,ATGP3082-1mg,ATGP3082-10,ATGP3082-20,ATGP3082-50,ATGP3082-100,ATGP3082-250,ATGP3082-500,ATGP3082-1

more info or order :

NKMAX product webpage