Recombinant human IL-17 RB protein | NKMAX ATGP3061 product information

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product summary

company name :

NKMAX

product type :

protein

product name :

Recombinant human IL-17 RB protein

catalog :

ATGP3061

quantity :

50 ug

price :

320 USD

product information

Product Type :

Proteins

Item Name :

Recombinant human IL-17 RB protein

Domain :

18-292aa

Catalog number (SKU) :

ATGP3061

NCBI :

NP_061195

Description :

IL17RB, also known as Interleukin-17 receptor B, is a cytokine receptor. This receptor specifically binds to IL17B and IL17E (IL25), but does not bind to IL17 (A) or IL17C. It has been shown to mediate the activation of NF-kappaB and the production of IL8 induced by IL17E. It was found to be significantly up-regulated during intestinal inflammation, which suggested the immunoregulatory activity of this receptor. Recombinant human IL17RB, fused to hIgG-His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.

Alternative Names :

Interleukin-17 receptor B, CRL4, EVI27, IL17BR, IL17RH1

Concentration :

0.25mg/ml (determined by Bradford assay)

Formulation :

Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol

Storage :

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

General References :

Ma XJ. et al. (2006) J Clin Oncol. 24:4611-4619

Purity :

> 85% by SDS-PAGE

Applications :

SDS-PAGE

Antigen Species :

Human

Gene Category :

Hormones & Cytokines

Molecular Weight :

57.2 kDa (514aa) Reducing conditions

Endotoxin :

< 1 EU per 1ug of protein (determined by LAL method)

Bioassay Procedure :

REPTVQCGSE TGPSPEWMLQ HDLIPGDLRD LRVEPVTTSV ATGDYSILMN VSWVLRADAS IRLLKATKIC VTGKSNFQSY SCVRCNYTEA FQTQTRPSGG KWTFSYIGFP VELNTVYFIG AHNIPNANMN EDGPSMSVNF TSPGCLDHIM KYKKKCVKAG SLWDPNITAC KKNEETVEVN FTTTPLGNRY MALIQHSTII GFSQVFEPHQ KKQTRASVVI PVTGDSEGAT VQLTPYFPTC GSDCIRHKGT VVLCPQTGVP FPLDNNKSKP GGWLP

Tag :

hIgG-His-Tag

Expression System :

Baculovirus

Product Type Name :

Recombinant Protein

UniProt No. :

Q9NRM6

Internal Search Terms :

IL17 RB, Interleukin-17 receptor B, CRL4, EVI27, IL17BR, IL17RH1

Size 2 :

50 ug

List Price 2 (USD) :

320 USD