Recombinant human MICA protein | NKMAX ATGP3053 product information

product summary

company name :

NKMAX

product type :

protein

product name :

Recombinant human MICA protein

catalog :

ATGP3053

quantity :

10 ug

price :

130 USD

more info or order :

NKMAX product webpage

product information

Product Type :

Proteins

Item Name :

Recombinant human MICA protein

Domain :

24-297aa

Catalog number (SKU) :

ATGP3053

NCBI :

AAH16929.1

Description :

MICA also known as MHC class I polypeptide-related sequence A. This Protein's Function seems to have no role in antigen presentation. It acts as a stress-induced self-antigen that is recognized by gamma delta T-cells. It binding to KLRK1 leads to cell lysis. Recombinant human MICA, fused to His-tag at C-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

Alternative Names :

MHC class I polypeptide-related sequence A, MHC class I polypeptide-related sequence A, PERB11.1, truncated

Concentration :

0.25mg/ml (determined by Bradford assay)

Formulation :

Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 1mM DTT, 10% Glycerol

Storage :

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

General References :

Strausberg, R.L, et al. (2002) Proc. Natl. Acad. Sci. u.S.A. 99 (26), 16899-16903

Purity :

> 90% by SDS-PAGE

Bioactivity Comment Only :

Measured by its binding ability in a functional ELISA with Human NKG2D (CAT# ATGP3662)

Applications :

SDS-PAGE, Bioactivity

Antigen Species :

Human

Gene Category :

Immunology

Molecular Weight :

32.7 kDa (283aa) confirmed by MALDI-TOF

Endotoxin :

< 1 EU per 1ug of protein (determined by LAL method)

Bioactivity Comment and Pics :

Human MICA is coated at 10 ug/ml (100 ul/well) can bind Human NKG2D (CAT# ATGP3662) in a Functional ELISA assay.

Amino Acid Sequence :

MEPHSLRYNL TVLSWDGSVQ SGFLTEVHLD GQPFLRCDRQ KCRAKPQGQW AEDVLGNKTW DRETRDLTGN GKDLRMTLAH IKDQKEGLHS LQEIRVCEIH EDNSTRSSQH FYYDGELFLS QNLETEEWTM PQSSRAQTLA MNVRNFLKED AMKTKTHYHA MHADCLQELR RYLKSGVVLR RTVPPMVNVT RSEASEGNIT VTCRASGFYP WNITLSWRQD GVSLSHDTQQ WGDVLPDGNG TYQTWVATRI CQGEEQRFTC YMEHSGNHST HPVPS

Tag :

His-Tag

Expression System :

E.coli

Product Type Name :

Recombinant Protein

UniProt No. :

Q29983

Internal Search Terms :

MICA, MHC class I polypeptide-related sequence A, MHC class I polypeptide-related sequence A, PERB11.1, truncated,ATGP3053-10ug,ATGP3053-20ug,ATGP3053-50ug,ATGP3053-100ug,ATGP3053-250ug,ATGP3053-500ug,ATGP3053-1mg,ATGP3053-10,ATGP3053-20,ATGP3053-50,ATGP3053-100,ATGP3053-250,ATGP3053-500,ATGP3053-1

more info or order :

NKMAX product webpage