product summary
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company name :
NKMAX
product type :
protein
product name :
Recombinant human RPRD1B protein
catalog :
ATGP3048
quantity :
20 ug
price :
80 USD
more info or order :
product information
Product Type :
Proteins
Item Name :
Recombinant human RPRD1B protein
Domain :
1-326aa
Catalog number (SKU) :
ATGP3048
NCBI :
NP_067038.1
Description :
RPRD1B also known as regulation of nuclear pre-mRNA domain-containing protein 1B. This protein interacts with phosphorylated C-terminal heptapeptide repeat domain (CTD) of the largest RNA polymerase II subunit POLR2A, and participates in dephosphorylation of the CTD. It promotes binding of RNA polymerase II to the CCDN1 promoter and to the termination region before the poly-A site but decreases its binding after the poly-A site. It prevents RNA polymerase II from reading through the 3' end termination site and may allow it to be recruited back to the promoter through promotion of the formation of a chromatin loop. It also enhances the transcription of a number of other cell cycle-related genes including CDK2, CDK4, CDK6 and cyclin-E but not CDKN1A, CDKN1B or cyclin-A. It promotes cell proliferation. Recombinant human RPRD1B, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.
Alternative Names :
Regulation of nuclear pre-mRNA domain-containing protein 1B, Regulation of nuclear pre-mRNA domain-containing protein 1B, C20orf77, CREPT, dJ1057B20.2, NET60
Concentration :
1mg/ml (determined by Bradford assay)
Formulation :
Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 20% glycerol
Storage :
Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
General References :
Lu D., et al. (2012) Cancer Cell 21:92-104
Purity :
> 90% by SDS-PAGE
Applications :
SDS-PAGE
Antigen Species :
Human
Gene Category :
Other
Molecular Weight :
39.3 kDa (349aa) confirmed by MALDI-TOF
Amino Acid Sequence :
MSSFSES ALEKKLSELS NSQQSVQTLS LWLIHHRKHA GPIVSVWHRE LRKAKSNRKL TFLYLANDVI QNSKRKGPEF TREFESVLVD AFSHVAREAD EGCKKPLERL LNIWQERSVY GGEFIQQLKL SMEDSKSPPP KATEEKKSLK RTFQQIQEEE DDDYPGSYSP QDPSAGPLLT EELIKALQDL ENAASGDATV RQKIASLPQE VQDVSLLEKI TDKEAAERLS KTVDEACLLL AEYNGRLAAE LEDRRQLARM LVEYTQNQKD VLSEKEKKLE EYKQKLARVT QVRKELKSHI QSLPDLSLLP NVTGGLAPLP SAGDLFSTD
Tag :
His-Tag
Expression System :
E.coli
Product Type Name :
Recombinant Protein
UniProt No. :
Q9NQG5
Internal Search Terms :
RPRD1B, Regulation of nuclear pre-mRNA domain-containing protein 1B, Regulation of nuclear pre-mRNA domain-containing protein 1B, C20orf77, CREPT, dJ1057B20.2, NET60,ATGP3048-10ug,ATGP3048-20ug,ATGP3048-50ug,ATGP3048-100ug,ATGP3048-250ug,ATGP3048-500ug,ATGP3048-1mg,ATGP3048-10,ATGP3048-20,ATGP3048-50,ATGP3048-100,ATGP3048-250,ATGP3048-500,ATGP3048-1
more info or order :
company information
NKMAX
SNUH Health Care Innovation Park 6F
172 Dolma-ro, Bundang-gu
Seongnam-si, Gyeonggi-do
https://www.nkmaxbio.com172 Dolma-ro, Bundang-gu
Seongnam-si, Gyeonggi-do
82-31-8017-8114
headquarters: South Korea
NKMAX Co. Ltd. is a biotech company that manufactures and supplies a unique line of quality proteins and antibodies worldwide to both researchers and retailers.